dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001549
Uniprot Accession O43482; MS18B_HUMAN; Q96BX7;
Genbank Protein ID NP_009211.1;
Genbank Nucleotide ID NM_007280.1;
Protein Name Protein Mis18-beta
Protein Synonyms/Alias Cancer/testis antigen 86;CT86;Opa-interacting protein 5;OIP-5;
Gene Name OIP5
Gene Synonyms/Alias MIS18B;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
Phosphorylation Sites
 dbPAF PTMs: 6
PositionPeptidesSourceReferences ( PMIDs )
10AQPLRHRSRCATPPRcurated23898821; 26074081
14RHRSRCATPPRGDFCdbPTM 3.0;PhosphoSitePlus;curated20736484; 16381945; 23193290; 22135298; 25627689; 23917254;
47DTQVVKGSSPLGPAGdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;curated18669648; 16381945; 23193290; 19664995; 19690332; 18691976;
48TQVVKGSSPLGPAGLdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;UniProt;curated19690332; 16381945; 23193290; 18669648; 19664995; 18988627;
221MKILSEVTPDQSKPEdbPTM 3.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;UniProt;curated19690332; 16381945; 23193290; 19664995; 20068231; 22115753;
225SEVTPDQSKPEN---dbPTM 3.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;UniProt;curated19690332; 16381945; 23193290; 20068231; 21406692; 22115753;
Sequence
(Fasta)		MAAQPLRHRS RCATPPRGDF CGGTERAIDQ ASFTTSMEWD TQVVKGSSPL GPAGLGAEEP 60
AAGPQLPSWL QPERCAVFQC AQCHAVLADS VHLAWDLSRS LGAVVFSRVT NNVVLEAPFL 120
VGIEGSLKGS TYNLLFCGSC GIPVGFHLYS THAALAALRG HFCLSSDKMV CYLLKTKAIV 180
NASEMDIQNV PLSEKIAELK EKIVLTHNRL KSLMKILSEV TPDQSKPEN
Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0137--Centromere
KW-0158--Chromosome
KW-0181--Complete proteome
KW-0498--Mitosis
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR004910--Yippee/Mis18
PROSITE
Pfam

PF03226--Yippee-Mis18
Gene Ontology

GO:0015030--C:Cajal body
GO:0000785--C:chromatin
GO:0010369--C:chromocenter
GO:0000775--C:chromosome, centromeric region
GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0007154--P:cell communication
GO:0051301--P:cell division
GO:0034080--P:CENP-A containing nucleosome assembly
GO:0007067--P:mitotic nuclear division
GO:0006334--P:nucleosome assembly