dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001543
Uniprot Accession O43448; KCAB3_HUMAN; Q4VAW0;
Genbank Protein ID NP_004723.2;
Genbank Nucleotide ID NM_004732.3;
Protein Name Voltage-gated potassium channel subunit beta-3
Protein Synonyms/Alias K(+) channel subunit beta-3;Kv-beta-3;
Gene Name KCNAB3
Gene Synonyms/Alias KCNA3B;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv1.5.
Phosphorylation Sites
dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
184IIEGLRGSLERLQLGdbPTM 3.0;HPRD 9;curated17081983; 16381945; 23193290; 18988627; 24260401
285GVGSVTWYPLACGLIPhosphoSitePlus22135298
293PLACGLITSKYDGRVPhosphoSitePlus22135298
294LACGLITSKYDGRVPPhosphoSitePlus22135298
Sequence
(Fasta)
MQVSIACTEQ NLRSRSSEDR LCGPRPGPGG GNGGPAGGGH GNPPGGGGSG PKARAALVPR 60
PPAPAGALRE STGRGTGMKY RNLGKSGLRV SCLGLGTWVT FGSQISDETA EDVLTVAYEH 120
GVNLFDTAEV YAAGKAERTL GNILKSKGWR RSSYVITTKI FWGGQAETER GLSRKHIIEG 180
LRGSLERLQL GYVDIVFANR SDPNCPMEEI VRAMTYVINQ GLALYWGTSR WGAAEIMEAY 240
SMARQFNLIP PVCEQAEHHL FQREKVEMQL PELYHKIGVG SVTWYPLACG LITSKYDGRV 300
PDTCRASIKG YQWLKDKVQS EDGKKQQAKV MDLLPVAHQL GCTVAQLAIA WCLRSEGVSS 360
VLLGVSSAEQ LIEHLGALQV LSQLTPQTVM EIDGLLGNKP HSKK 405
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0407--Ion channel
KW-0406--Ion transport
KW-0630--Potassium
KW-0633--Potassium transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0851--Voltage-gated channel

Interpro

IPR001395--Aldo/ket_red/Kv-b
IPR005983--K_chnl_volt-dep_bsu_KCNAB
IPR005399--K_chnl_volt-dep_bsu_KCNAB-rel
IPR005402--K_chnl_volt-dep_bsu_KCNAB3
IPR023210--NADP_OxRdtase_dom

PROSITE
Pfam

PF00248--Aldo_ket_red

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0015459--F:potassium channel regulator activity
GO:0005249--F:voltage-gated potassium channel activity
GO:0006813--P:potassium ion transport
GO:0007268--P:synaptic transmission