dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001538
Uniprot Accession O43427; FIBP_HUMAN; A8K0J7; Q27Q85; Q6IBQ3; Q9HD65;
Genbank Protein ID NP_004205.2; NP_942600.1;
Genbank Nucleotide ID NM_004214.4; NM_198897.1;
Protein Name Acidic fibroblast growth factor intracellular-binding protein
Protein Synonyms/Alias
Gene Name FIBP
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
May be involved in mitogenic function of FGF1. May mediate with IER2 FGF-signaling in the establishment of laterality in the embryo (By similarity).
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
2------MTSELDIFVdbPTM 3.019369195; 16381945; 23193290
127LDDISTKTGITLKSCcurated26074081
130ISTKTGITLKSCRRQcurated26074081
Sequence
(Fasta)
MTSELDIFVG NTTLIDEDVY RLWLDGYSVT DAVALRVRSG ILEQTGATAA VLQSDTMDHY 60
RTFHMLERLL HAPPKLLHQL IFQIPPSRQA LLIERYYAFD EAFVREVLGK KLSKGTKKDL 120
DDISTKTGIT LKSCRRQFDN FKRVFKVVEE MRGSLVDNIQ QHFLLSDRLA RDYAAIVFFA 180
NNRFETGKKK LQYLSFGDFA FCAELMIQNW TLGAVGEAPT DPDSQMDDMD MDLDKEFLQD 240
LKELKVLVAD KDLLDLHKSL VCTALRGKLG VFSEMEANFK NLSRGLVNVA AKLTHNKDVR 300
DLFVDLVEKF VEPCRSDHWP LSDVRFFLNQ YSASVHSLDG FRHQALWDRY MGTLRGCLLR 360
LYHD 365
Keyword

KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0472--Membrane
KW-0539--Nucleus
KW-0621--Polymorphism
KW-1185--Reference proteome

Interpro

IPR008614--FIBP

PROSITE
Pfam

PF05427--FIBP

Gene Ontology

GO:0012505--C:endomembrane system
GO:0070062--C:extracellular exosome
GO:0016020--C:membrane
GO:0005739--C:mitochondrion
GO:0005634--C:nucleus
GO:0017134--F:fibroblast growth factor binding
GO:0008543--P:fibroblast growth factor receptor signaling pathway
GO:0070527--P:platelet aggregation