dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001533
Uniprot Accession O43414; ERI3_HUMAN; B1AK98; Q5T2T7; Q5T2T9; Q5TG35; Q9BQA0; Q9UEB4;
Genbank Protein ID NP_001288627.1; NP_001288628.1; NP_001288629.1; NP_001288630.1; NP_076971.1;
Genbank Nucleotide ID NM_001301698.1; NM_001301699.1; NM_001301700.1; NM_001301701.1; NM_024066.2;
Protein Name ERI1 exoribonuclease 3
Protein Synonyms/Alias Prion interactor 1;Prion protein-interacting protein;
Gene Name ERI3
Gene Synonyms/Alias PINT1;PRNPIP;PRNPIP1;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
104RARKVLGSHLFSPCGPhosphoSitePlus22135298
Sequence
(Fasta)
MATASPAADG GRGRPWEGGL VSWPPAPPLT LPWTWMGPSW GQHPGHWGFP ALTEPSASPA 60
AGLGIFEVRR VLDASGCSML APLQTGAARF SSYLLSRARK VLGSHLFSPC GVPEFCSIST 120
RKLAAHGFGA SMAAMVSFPP QRYHYFLVLD FEATCDKPQI HPQEIIEFPI LKLNGRTMEI 180
ESTFHMYVQP VVHPQLTPFC TELTGIIQAM VDGQPSLQQV LERVDEWMAK EGLLDPNVKS 240
IFVTCGDWDL KVMLPGQCQY LGLPVADYFK QWINLKKAYS FAMGCWPKNG LLDMNKGLSL 300
QHIGRPHSGI DDCKNIANIM KTLAYRGFIF KQTSKPF 338
Keyword

KW-0002--3D-structure
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0269--Exonuclease
KW-0378--Hydrolase
KW-0460--Magnesium
KW-0479--Metal-binding
KW-0540--Nuclease
KW-1185--Reference proteome

Interpro

IPR013520--Exonuclease_RNaseT/DNA_pol3
IPR012337--RNaseH-like_dom

PROSITE
Pfam

PF00929--RNase_T

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005730--C:nucleolus
GO:0000175--F:3'-5'-exoribonuclease activity
GO:0046872--F:metal ion binding
GO:0044822--F:poly(A) RNA binding
GO:0000738--P:DNA catabolic process, exonucleolytic
GO:0000467--P:exonucleolytic trimming to generate mature 3'-end of 5
8S rRNA fr--m tricistronic rRNA transcript (SSU-rRNA, 5
8S rRNA, L--U-rRNA)