Tag |
Content |
dbPAF ID |
dbPAF-0001524 |
Uniprot Accession |
O43365; HXA3_HUMAN; A4D181; |
Genbank Protein ID |
NP_109377.1; NP_705895.1; XP_005249787.1; XP_005249788.1; XP_005249789.1; XP_006715778.1; XP_011513645.1; |
Genbank Nucleotide ID |
NM_030661.4; NM_153631.2; XM_005249730.2; XM_005249731.2; XM_005249732.3; XM_006715715.2; XM_011515343.1; |
Protein Name |
Homeobox protein Hox-A3 |
Protein Synonyms/Alias |
Homeobox protein Hox-1E; |
Gene Name |
HOXA3 |
Gene Synonyms/Alias |
HOX1E; |
Organism |
Homo sapiens(Human) |
NCBI Taxa ID |
9606 |
Functional Description (View all) |
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.Functional Description
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
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Phosphorylation Sites
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dbPAF PTMs: 6 |
Sequence (Fasta) | MQKATYYDSS AIYGGYPYQA ANGFAYNANQ QPYPASAALG ADGEYHRPAC SLQSPSSAGG 60 HPKAHELSEA CLRTLSAPPS QPPSLGEPPL HPPPPQAAPP APQPPQPAPQ PPAPTPAAPP 120 PPSSASPPQN ASNNPTPANA AKSPLLNSPT VAKQIFPWMK ESRQNTKQKT SSSSSGESCA 180 GDKSPPGQAS SKRARTAYTS AQLVELEKEF HFNRYLCRPR RVEMANLLNL TERQIKIWFQ 240 NRRMKYKKDQ KGKGMLTSSG GQSPSRSPVP PGAGGYLNSM HSLVNSVPYE PQSPPPFSKP 300 PQGTYGLPPA SYPASLPSCA PPPPPQKRYT AAGAGAGGTP DYDPHAHGLQ GNGSYGTPHI 360 QGSPVFVGGS YVEPMSNSGP ALFGLTHLPH AASGAMDYGG AGPLGSGHHH GPGPGEPHPT 420 YTDLTGHHPS QGRIQEAPKL THL
444Fasta Sequence
>O43365|HOXA3|Homo sapiens(Human) MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPPPPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGHHHGPGPGEPHPTYTDLTGHHPSQGRIQEAPKLTHL
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Keyword |
KW-0181--Complete proteome KW-0217--Developmental protein KW-0238--DNA-binding KW-0371--Homeobox KW-0539--Nucleus KW-0621--Polymorphism KW-1185--Reference proteome KW-0804--Transcription KW-0805--Transcription regulation
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Interpro |
IPR025281--DUF4074 IPR001827--Homeobox_Antennapedia_CS IPR017970--Homeobox_CS IPR001356--Homeobox_dom IPR020479--Homeobox_metazoa IPR009057--Homeodomain-like
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PROSITE |
PS00032--ANTENNAPEDIA PS00027--HOMEOBOX_1 PS50071--HOMEOBOX_2
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Pfam |
PF13293--DUF4074 PF00046--Homeobox
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Gene Ontology |
GO:0005654--C:nucleoplasm GO:0043565--F:sequence-specific DNA binding GO:0003700--F:transcription factor activity, sequence-specific DNA binding GO:0001525--P:angiogenesis GO:0009952--P:anterior/posterior pattern specification GO:0001974--P:blood vessel remodeling GO:0051216--P:cartilage development GO:0048704--P:embryonic skeletal system morphogenesis GO:0021615--P:glossopharyngeal nerve morphogenesis GO:0048645--P:organ formation GO:0060017--P:parathyroid gland development GO:0008284--P:positive regulation of cell proliferation GO:0010159--P:specification of organ position GO:0048538--P:thymus development GO:0030878--P:thyroid gland development GO:0006351--P:transcription, DNA-templated
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