| Tag |
Content |
| dbPAF ID |
dbPAF-0001523 |
| Uniprot Accession |
O43364; HXA2_HUMAN; A1L4K3; B2RMW3;
|
| Genbank Protein ID |
NP_006726.1;
|
| Genbank Nucleotide ID |
NM_006735.3;
|
| Protein Name |
Homeobox protein Hox-A2 |
| Protein Synonyms/Alias |
Homeobox protein Hox-1K; |
| Gene Name |
HOXA2 |
| Gene Synonyms/Alias |
HOX1K; |
| Organism |
Homo sapiens(Human) |
| NCBI Taxa ID |
9606 |
Functional Description
(View all) |
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.Functional Description
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. |
Phosphorylation Sites
|
dbPAF PTMs: 5 |
Sequence
(Fasta) | MNYEFEREIG FINSQPSLAE CLTSFPPVAD TFQSSSIKTS TLSHSTLIPP PFEQTIPSLN 60
PGSHPRHGAG GRPKPSPAGS RGSPVPAGAL QPPEYPWMKE KKAAKKTALL PAAAAAATAA 120
ATGPACLSHK ESLEIADGSG GGSRRLRTAY TNTQLLELEK EFHFNKYLCR PRRVEIAALL 180
DLTERQVKVW FQNRRMKHKR QTQCKENQNS EGKCKSLEDS EKVEEDEEEK TLFEQALSVS 240
GALLEREGYT FQQNALSQQQ APNGHNGDSQ SFPVSPLTSN EKNLKHFQHQ SPTVPNCLST 300
MGQNCGAGLN NDSPEALEVP SLQDFSVFST DSCLQLSDAV SPSLPGSLDS PVDISADSLD 360
FFTDTLTTID LQHLNY
377Fasta Sequence
>O43364|HOXA2|Homo sapiens(Human)
MNYEFEREIGFINSQPSLAECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLNPGSHPRHGAGGRPKPSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATAAATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKCKSLEDSEKVEEDEEEKTLFEQALSVSGALLEREGYTFQQNALSQQQAPNGHNGDSQSFPVSPLTSNEKNLKHFQHQSPTVPNCLSTMGQNCGAGLNNDSPEALEVPSLQDFSVFSTDSCLQLSDAVSPSLPGSLDSPVDISADSLDFFTDTLTTIDLQHLNY
|
| Keyword |
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0225--Disease mutation
KW-0238--DNA-binding
KW-0371--Homeobox
KW-0539--Nucleus
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
|
| Interpro |
IPR001827--Homeobox_Antennapedia_CS
IPR017970--Homeobox_CS
IPR001356--Homeobox_dom
IPR020479--Homeobox_metazoa
IPR009057--Homeodomain-like
|
| PROSITE |
PS00032--ANTENNAPEDIA
PS00027--HOMEOBOX_1
PS50071--HOMEOBOX_2
|
| Pfam |
PF00046--Homeobox
|
| Gene Ontology |
GO:0005654--C:nucleoplasm
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0009952--P:anterior/posterior pattern specification
GO:0035284--P:brain segmentation
GO:0001709--P:cell fate determination
GO:0071300--P:cellular response to retinoic acid
GO:0009953--P:dorsal/ventral pattern formation
GO:0048703--P:embryonic viscerocranium morphogenesis
GO:0042474--P:middle ear morphogenesis
GO:0008045--P:motor neuron axon guidance
GO:0045665--P:negative regulation of neuron differentiation
GO:0045668--P:negative regulation of osteoblast differentiation
GO:0002076--P:osteoblast development
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0021568--P:rhombomere 2 development
GO:0021658--P:rhombomere 3 morphogenesis
GO:0007379--P:segment specification
GO:0006351--P:transcription, DNA-templated
|
