dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001518
Uniprot Accession O43324; MCA3_HUMAN; C9JLK5; Q5THS2;
Genbank Protein ID NP_001129122.1; NP_004271.1;
Genbank Nucleotide ID NM_001135650.1; NM_004280.4;
Protein Name Eukaryotic translation elongation factor 1 epsilon-1
Protein Synonyms/Alias Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3;Elongation factor p18;Multisynthase complex auxiliary component p18;
Gene Name EEF1E1
Gene Synonyms/Alias AIMP3;P18;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Positive modulator of ATM response to DNA damage.
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
8MAAAAELSLLEKSLGdbPTM 3.020068231; 16381945; 23193290
173KNRLYTNSH------curated25849741
Sequence
(Fasta)		MAAAAELSLL EKSLGLSKGN KYSAQGERQI PVLQTNNGPS LTGLTTIAAH LVKQANKEYL 60
LGSTAEEKAI VQQWLEYRVT QVDGHSSKND IHTLLKDLNS YLEDKVYLTG YNFTLADILL 120
YYGLHRFIVD LTVQEKEKYL NVSRWFCHIQ HYPGIRQHLS SVVFIKNRLY TNSH 175
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0539--Nucleus
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
Interpro

IPR010987--Glutathione-S-Trfase_C-like
IPR004046--GST_C
PROSITE

PS50405--GST_CTER
Pfam

PF14497--GST_C_3
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0004364--F:glutathione transferase activity
GO:0003746--F:translation elongation factor activity
GO:0010467--P:gene expression
GO:0006749--P:glutathione metabolic process
GO:0008285--P:negative regulation of cell proliferation
GO:0043065--P:positive regulation of apoptotic process
GO:0043517--P:positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0006414--P:translational elongation
GO:0006418--P:tRNA aminoacylation for protein translation