dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001493
Uniprot Accession O43286; B4GT5_HUMAN; E1P625; Q2M394; Q9UJQ8;
Genbank Protein ID NP_004767.1;
Genbank Nucleotide ID NM_004776.3;
Protein Name Beta-1,4-galactosyltransferase 5
Protein Synonyms/Alias
Gene Name B4GALT5
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.
Phosphorylation Sites
dbPAF PTMs: 6
PositionPeptidesSourceReferences ( PMIDs )
59LIRDNVRTIGAQVYEPhosphoSitePlus22135298
71VYEQVLRSAYAKRNSPhosphoSitePlus22135298
73EQVLRSAYAKRNSSVPhosphoSitePlus22135298
156LGGHWKPSDCMPRWKcurated26074081
375DALYKNITVNLTPELPhosphoSitePlus22135298
388ELAQVNEY-------PhosphoSitePlus22135298
Sequence
(Fasta)
MRARRGLLRL PRRSLLAALF FFSLSSSLLY FVYVAPGIVN TYLFMMQAQG ILIRDNVRTI 60
GAQVYEQVLR SAYAKRNSSV NDSDYPLDLN HSETFLQTTT FLPEDFTYFA NHTCPERLPS 120
MKGPIDINMS EIGMDYIHEL FSKDPTIKLG GHWKPSDCMP RWKVAILIPF RNRHEHLPVL 180
FRHLLPMLQR QRLQFAFYVV EQVGTQPFNR AMLFNVGFQE AMKDLDWDCL IFHDVDHIPE 240
SDRNYYGCGQ MPRHFATKLD KYMYLLPYTE FFGGVSGLTV EQFRKINGFP NAFWGWGGED 300
DDLWNRVQNA GYSVSRPEGD TGKYKSIPHH HRGEVQFLGR YALLRKSKER QGLDGLNNLN 360
YFANITYDAL YKNITVNLTP ELAQVNEY 389
Keyword

KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0325--Glycoprotein
KW-0328--Glycosyltransferase
KW-0333--Golgi apparatus
KW-0464--Manganese
KW-0472--Membrane
KW-0479--Metal-binding
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0735--Signal-anchor
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003859--Galactosyl_T
IPR027791--Galactosyl_T_C
IPR027995--Galactosyl_T_N
IPR029044--Nucleotide-diphossugar_trans

PROSITE
Pfam

PF02709--Glyco_transf_7C
PF13733--Glyco_transf_7N

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0032580--C:Golgi cisterna membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0008378--F:galactosyltransferase activity
GO:0046872--F:metal ion binding
GO:0005975--P:carbohydrate metabolic process
GO:0044267--P:cellular protein metabolic process
GO:0030203--P:glycosaminoglycan metabolic process
GO:0018146--P:keratan sulfate biosynthetic process
GO:0042339--P:keratan sulfate metabolic process
GO:0016266--P:O-glycan processing
GO:0043687--P:post-translational protein modification
GO:0018279--P:protein N-linked glycosylation via asparagine
GO:0006493--P:protein O-linked glycosylation
GO:0044281--P:small molecule metabolic process