dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001490
Uniprot Accession O43280; TREA_HUMAN; Q32MB9; Q53FY8;
Genbank Protein ID NP_001287994.1; NP_009111.2;
Genbank Nucleotide ID NM_001301065.1; NM_007180.2;
Protein Name Trehalase
Protein Synonyms/Alias Alpha,alpha-trehalase;Alpha,alpha-trehalose glucohydrolase;
Gene Name TREH
Gene Synonyms/Alias TREA;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose.
Phosphorylation Sites
dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
112TPADWKDSPQFLQKIPhosphoSitePlus22135298
154LSHPERFSLIYSEHPPhosphoSitePlus22135298
278KNYLLNRYYVPYGGPPhosphoSitePlus22135298
282LNRYYVPYGGPRPESPhosphoSitePlus22135298
371YSRLGNDSQATKYRIPhosphoSitePlus22135298
374LGNDSQATKYRILRSPhosphoSitePlus22135298
376NDSQATKYRILRSQRPhosphoSitePlus22135298
Sequence
(Fasta)
MPGRTWELCL LLLLGLGLGS QEALPPPCES EIYCHGELLN QVQMAKLYQD DKQFVDMPLS 60
IAPEQVLQTF TELSRDHNHS IPREQLQAFV HEHFQAKGQE LQPWTPADWK DSPQFLQKIS 120
DAKLRAWAGQ LHQLWKKLGK KMKPEVLSHP ERFSLIYSEH PFIVPGGRFV EFYYWDSYWV 180
MEGLLLSEMA ETVKGMLQNF LDLVKTYGHV PNGGRVYYLQ RSQPPLLTLM MDCYLTHTND 240
TAFLQENIET LALELDFWTK NRTVSVSLEG KNYLLNRYYV PYGGPRPESY SKDVELADTL 300
PEGDREALWA ELKAGAESGW DFSSRWLIGG PNPNSLSGIR TSKLVPVDLN AFLCQAEELM 360
SNFYSRLGND SQATKYRILR SQRLAALNTV LWDEQTGAWF DYDLEKKKKN REFYPSNLTP 420
LWAGCFSDPG VADKALKYLE DNRILTYQYG IPTSLQKTGQ QWDFPNAWAP LQDLVIRGLA 480
KAPLRRAQEV AFQLAQNWIR TNFDVYSQKS AMYEKYDVSN GGQPGGGGEY EVQEGFGWTN 540
GVVLMLLDRY GDRLTSGAKL AFLEPHCLAA TLLPSLLLSL LPW 584
Keyword

KW-0025--Alternative splicing
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-1015--Disulfide bond
KW-0325--Glycoprotein
KW-0326--Glycosidase
KW-0336--GPI-anchor
KW-0378--Hydrolase
KW-0449--Lipoprotein
KW-0472--Membrane
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0732--Signal

Interpro

IPR008928--6-hairpin_glycosidase-like
IPR001661--Glyco_hydro_37
IPR018232--Glyco_hydro_37_CS

PROSITE

PS00927--TREHALASE_1
PS00928--TREHALASE_2

Pfam

PF01204--Trehalase

Gene Ontology

GO:0046658--C:anchored component of plasma membrane
GO:0070062--C:extracellular exosome
GO:0005886--C:plasma membrane
GO:0004555--F:alpha,alpha-trehalase activity
GO:0005975--P:carbohydrate metabolic process
GO:0009887--P:organ morphogenesis
GO:0044245--P:polysaccharide digestion
GO:0044281--P:small molecule metabolic process
GO:0005993--P:trehalose catabolic process
GO:0005991--P:trehalose metabolic process