Tag |
Content |
dbPAF ID |
dbPAF-0001490 |
Uniprot Accession |
O43280; TREA_HUMAN; Q32MB9; Q53FY8; |
Genbank Protein ID |
NP_001287994.1; NP_009111.2; |
Genbank Nucleotide ID |
NM_001301065.1; NM_007180.2; |
Protein Name |
Trehalase |
Protein Synonyms/Alias |
Alpha,alpha-trehalase;Alpha,alpha-trehalose glucohydrolase; |
Gene Name |
TREH |
Gene Synonyms/Alias |
TREA; |
Organism |
Homo sapiens(Human) |
NCBI Taxa ID |
9606 |
Functional Description (View all) |
Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose.Functional Description
Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose.
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Phosphorylation Sites
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dbPAF PTMs: 7 Position | Peptides | Source | References ( PMIDs ) |
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112 | TPADWKDSPQFLQKI | PhosphoSitePlus | 22135298 | 154 | LSHPERFSLIYSEHP | PhosphoSitePlus | 22135298 | 278 | KNYLLNRYYVPYGGP | PhosphoSitePlus | 22135298 | 282 | LNRYYVPYGGPRPES | PhosphoSitePlus | 22135298 | 371 | YSRLGNDSQATKYRI | PhosphoSitePlus | 22135298 | 374 | LGNDSQATKYRILRS | PhosphoSitePlus | 22135298 | 376 | NDSQATKYRILRSQR | PhosphoSitePlus | 22135298 |
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Sequence (Fasta) | MPGRTWELCL LLLLGLGLGS QEALPPPCES EIYCHGELLN QVQMAKLYQD DKQFVDMPLS 60 IAPEQVLQTF TELSRDHNHS IPREQLQAFV HEHFQAKGQE LQPWTPADWK DSPQFLQKIS 120 DAKLRAWAGQ LHQLWKKLGK KMKPEVLSHP ERFSLIYSEH PFIVPGGRFV EFYYWDSYWV 180 MEGLLLSEMA ETVKGMLQNF LDLVKTYGHV PNGGRVYYLQ RSQPPLLTLM MDCYLTHTND 240 TAFLQENIET LALELDFWTK NRTVSVSLEG KNYLLNRYYV PYGGPRPESY SKDVELADTL 300 PEGDREALWA ELKAGAESGW DFSSRWLIGG PNPNSLSGIR TSKLVPVDLN AFLCQAEELM 360 SNFYSRLGND SQATKYRILR SQRLAALNTV LWDEQTGAWF DYDLEKKKKN REFYPSNLTP 420 LWAGCFSDPG VADKALKYLE DNRILTYQYG IPTSLQKTGQ QWDFPNAWAP LQDLVIRGLA 480 KAPLRRAQEV AFQLAQNWIR TNFDVYSQKS AMYEKYDVSN GGQPGGGGEY EVQEGFGWTN 540 GVVLMLLDRY GDRLTSGAKL AFLEPHCLAA TLLPSLLLSL LPW
584Fasta Sequence
>O43280|TREH|Homo sapiens(Human) MPGRTWELCLLLLLGLGLGSQEALPPPCESEIYCHGELLNQVQMAKLYQDDKQFVDMPLSIAPEQVLQTFTELSRDHNHSIPREQLQAFVHEHFQAKGQELQPWTPADWKDSPQFLQKISDAKLRAWAGQLHQLWKKLGKKMKPEVLSHPERFSLIYSEHPFIVPGGRFVEFYYWDSYWVMEGLLLSEMAETVKGMLQNFLDLVKTYGHVPNGGRVYYLQRSQPPLLTLMMDCYLTHTNDTAFLQENIETLALELDFWTKNRTVSVSLEGKNYLLNRYYVPYGGPRPESYSKDVELADTLPEGDREALWAELKAGAESGWDFSSRWLIGGPNPNSLSGIRTSKLVPVDLNAFLCQAEELMSNFYSRLGNDSQATKYRILRSQRLAALNTVLWDEQTGAWFDYDLEKKKKNREFYPSNLTPLWAGCFSDPGVADKALKYLEDNRILTYQYGIPTSLQKTGQQWDFPNAWAPLQDLVIRGLAKAPLRRAQEVAFQLAQNWIRTNFDVYSQKSAMYEKYDVSNGGQPGGGGEYEVQEGFGWTNGVVLMLLDRYGDRLTSGAKLAFLEPHCLAATLLPSLLLSLLPW
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Keyword |
KW-0025--Alternative splicing KW-1003--Cell membrane KW-0181--Complete proteome KW-0903--Direct protein sequencing KW-1015--Disulfide bond KW-0325--Glycoprotein KW-0326--Glycosidase KW-0336--GPI-anchor KW-0378--Hydrolase KW-0449--Lipoprotein KW-0472--Membrane KW-0621--Polymorphism KW-1185--Reference proteome KW-0732--Signal
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Interpro |
IPR008928--6-hairpin_glycosidase-like IPR001661--Glyco_hydro_37 IPR018232--Glyco_hydro_37_CS
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PROSITE |
PS00927--TREHALASE_1 PS00928--TREHALASE_2
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Pfam |
PF01204--Trehalase
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Gene Ontology |
GO:0046658--C:anchored component of plasma membrane GO:0070062--C:extracellular exosome GO:0005886--C:plasma membrane GO:0004555--F:alpha,alpha-trehalase activity GO:0005975--P:carbohydrate metabolic process GO:0009887--P:organ morphogenesis GO:0044245--P:polysaccharide digestion GO:0044281--P:small molecule metabolic process GO:0005993--P:trehalose catabolic process GO:0005991--P:trehalose metabolic process
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