dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001486
Uniprot Accession O43257; ZNHI1_HUMAN; Q6IB12;
Genbank Protein ID NP_006340.1;
Genbank Nucleotide ID NM_006349.2;
Protein Name Zinc finger HIT domain-containing protein 1
Protein Synonyms/Alias Cyclin-G1-binding protein 1;Zinc finger protein subfamily 4A member 1;p18 Hamlet;
Gene Name ZNHIT1
Gene Synonyms/Alias CGBP1;ZNFN4A1;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Seems to play a role in p53-mediated apoptosis induction. Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
103AEGPNYLTACAGPPSdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated17380123; 16381945; 23193290; 18988627; 22135298; 22817900
Sequence
(Fasta)		MVEKKTSVRS QDPGQRRVLD RAARQRRINR QLEALENDNF QDDPHAGLPQ LGKRLPQFDD 60
DADTGKKKKK TRGDHFKLRF RKNFQALLEE QNLSVAEGPN YLTACAGPPS RPQRPFCAVC 120
GFPSPYTCVS CGARYCTVRC LGTHQETRCL KWTV 155
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR007529--Znf_HIT
PROSITE

PS51083--ZF_HIT
Pfam

PF04438--zf-HIT
Gene Ontology

GO:0005634--C:nucleus
GO:0000812--C:Swr1 complex
GO:0042826--F:histone deacetylase binding
GO:0046872--F:metal ion binding
GO:0031491--F:nucleosome binding
GO:0043486--P:histone exchange
GO:0031063--P:regulation of histone deacetylation