| Tag |
Content |
| dbPAF ID |
dbPAF-0001482 |
| Uniprot Accession |
O43248; HXC11_HUMAN; A8K7D1; Q96DH2;
|
| Genbank Protein ID |
NP_055027.1;
|
| Genbank Nucleotide ID |
NM_014212.3;
|
| Protein Name |
Homeobox protein Hox-C11 |
| Protein Synonyms/Alias |
Homeobox protein Hox-3H; |
| Gene Name |
HOXC11 |
| Gene Synonyms/Alias |
HOX3H; |
| Organism |
Homo sapiens(Human) |
| NCBI Taxa ID |
9606 |
Functional Description
(View all) |
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to a promoter element of the lactase-phlorizin hydrolase gene.Functional Description
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to a promoter element of the lactase-phlorizin hydrolase gene. |
Phosphorylation Sites
|
dbPAF PTMs: 7 |
Sequence
(Fasta) | MFNSVNLGNF CSPSRKERGA DFGERGSCAS NLYLPSCTYY MPEFSTVSSF LPQAPSRQIS 60
YPYSAQVPPV REVSYGLEPS GKWHHRNSYS SCYAAADELM HRECLPPSTV TEILMKNEGS 120
YGGHHHPSAP HATPAGFYSS VNKNSVLPQA FDRFFDNAYC GGGDPPAEPP CSGKGEAKGE 180
PEAPPASGLA SRAEAGAEAE AEEENTNPSS SGSAHSVAKE PAKGAAPNAP RTRKKRCPYS 240
KFQIRELERE FFFNVYINKE KRLQLSRMLN LTDRQVKIWF QNRRMKEKKL SRDRLQYFSG 300
NPLL
305Fasta Sequence
>O43248|HOXC11|Homo sapiens(Human)
MFNSVNLGNFCSPSRKERGADFGERGSCASNLYLPSCTYYMPEFSTVSSFLPQAPSRQISYPYSAQVPPVREVSYGLEPSGKWHHRNSYSSCYAAADELMHRECLPPSTVTEILMKNEGSYGGHHHPSAPHATPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDPPAEPPCSGKGEAKGEPEAPPASGLASRAEAGAEAEAEEENTNPSSSGSAHSVAKEPAKGAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSRDRLQYFSGNPLL
|
| Keyword |
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0238--DNA-binding
KW-0371--Homeobox
KW-1017--Isopeptide bond
KW-0539--Nucleus
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0832--Ubl conjugation
|
| Interpro |
IPR021918--DUF3528
IPR017970--Homeobox_CS
IPR001356--Homeobox_dom
IPR020479--Homeobox_metazoa
IPR009057--Homeodomain-like
|
| PROSITE |
PS00027--HOMEOBOX_1
PS50071--HOMEOBOX_2
|
| Pfam |
PF12045--DUF3528
PF00046--Homeobox
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0009952--P:anterior/posterior pattern specification
GO:0042733--P:embryonic digit morphogenesis
GO:0060272--P:embryonic skeletal joint morphogenesis
GO:0007492--P:endoderm development
GO:0001656--P:metanephros development
GO:0001759--P:organ induction
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0009954--P:proximal/distal pattern formation
GO:0006366--P:transcription from RNA polymerase II promoter
|
