| Tag |
Content |
| dbPAF ID |
dbPAF-0001480 |
| Uniprot Accession |
O43246; CTR4_HUMAN; Q0P5U2; Q3KNQ6; Q4VC45; Q6IBY8; Q96H88;
|
| Genbank Protein ID |
NP_004164.2;
|
| Genbank Nucleotide ID |
NM_004173.2;
|
| Protein Name |
Cationic amino acid transporter 4 |
| Protein Synonyms/Alias |
|
| Gene Name |
SLC7A4 |
| Gene Synonyms/Alias |
|
| Organism |
Homo sapiens(Human) |
| NCBI Taxa ID |
9606 |
Functional Description
(View all) |
Involved in the transport of the cationic amino acids (arginine, lysine and ornithine).Functional Description
Involved in the transport of the cationic amino acids (arginine, lysine and ornithine). |
Phosphorylation Sites
|
dbPAF PTMs: 1 | Position | Peptides | Source | References ( PMIDs ) |
|---|
| 56 | GMVGSGLYVLTGAVA | PhosphoSitePlus | 22135298 |
|
Sequence
(Fasta) | MARGLPTIAS LARLCQKLNR LKPLEDSTME TSLRRCLSTL DLTLLGVGGM VGSGLYVLTG 60
AVAKEVAGPA VLLSFGVAAV ASLLAALCYA EFGARVPRTG SAYLFTYVSM GELWAFLIGW 120
NVLLEYIIGG AAVARAWSGY LDSMFSHSIR NFTETHVGSW QVPLLGHYPD FLAAGIILLA 180
SAFVSCGARV SSWLNHTFSA ISLLVILFIV ILGFILAQPH NWSADEGGFA PFGFSGVMAG 240
TASCFYAFVG FDVIAASSEE AQNPRRSVPL AIAISLAIAA GAYILVSTVL TLMVPWHSLD 300
PDSALADAFY QRGYRWAGFI VAAGSICAMN TVLLSLLFSL PRIVYAMAAD GLFFQVFAHV 360
HPRTQVPVAG TLAFGLLTAF LALLLDLESL VQFLSLGTLL AYTFVATSII VLRFQKSSPP 420
SSPGPASPGP LTKQQSSFSD HLQLVGTVHA SVPEPGELKP ALRPYLGFLD GYSPGAVVTW 480
ALGVMLASAI TIGCVLVFGN STLHLPHWGY ILLLLLTSVM FLLSLLVLGA HQQQYREDLF 540
QIPMVPLIPA LSIVLNICLM LKLSYLTWVR FSIWLLMGLA VYFGYGIRHS KENQRELPGL 600
NSTHYVVFPR GSLEETVQAM QPPSQAPAQD PGHME
636Fasta Sequence
>O43246|SLC7A4|Homo sapiens(Human)
MARGLPTIASLARLCQKLNRLKPLEDSTMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAVLLSFGVAAVASLLAALCYAEFGARVPRTGSAYLFTYVSMGELWAFLIGWNVLLEYIIGGAAVARAWSGYLDSMFSHSIRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLVILFIVILGFILAQPHNWSADEGGFAPFGFSGVMAGTASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSSPPSSPGPASPGPLTKQQSSFSDHLQLVGTVHASVPEPGELKPALRPYLGFLDGYSPGAVVTWALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVMFLLSLLVLGAHQQQYREDLFQIPMVPLIPALSIVLNICLMLKLSYLTWVRFSIWLLMGLAVYFGYGIRHSKENQRELPGLNSTHYVVFPRGSLEETVQAMQPPSQAPAQDPGHME
|
| Keyword |
KW-0029--Amino-acid transport
KW-0181--Complete proteome
KW-0325--Glycoprotein
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
|
| Interpro |
IPR002293--AA/rel_permease1
IPR029485--CAT_C
|
| PROSITE |
|
| Pfam |
PF13520--AA_permease_2
PF13906--AA_permease_C
|
| Gene Ontology |
GO:0016021--C:integral component of membrane
GO:0005887--C:integral component of plasma membrane
GO:0015297--F:antiporter activity
GO:0015181--F:arginine transmembrane transporter activity
GO:0015174--F:basic amino acid transmembrane transporter activity
GO:0015189--F:L-lysine transmembrane transporter activity
GO:0000064--F:L-ornithine transmembrane transporter activity
GO:1990822--P:basic amino acid transmembrane transport
GO:0006520--P:cellular amino acid metabolic process
GO:0097638--P:L-arginine import across plasma membrane
GO:1903401--P:L-lysine transmembrane transport
GO:1903352--P:L-ornithine transmembrane transport
GO:0006810--P:transport
|
