dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0001413 |
| Uniprot Accession | O42980; NESP1_SCHPO; P78807; |
| Genbank Protein ID | NP_596375.2; |
| Genbank Nucleotide ID | NM_001022296.2; |
| Protein Name | NEDD8-specific protease 1 |
| Protein Synonyms/Alias | |
| Gene Name | nep1 |
| Gene Synonyms/Alias | SPBC17D11.01;SPBC20F10.11; |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) |
| NCBI Taxa ID | 284812 |
| Functional Description (View all) |
Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as the pcu1, pcu2 and pcu4 cullins and other proteins. |
| Phosphorylation Sites |
dbPAF PTMs: 3 |
| Sequence (Fasta) | MSSSPTVLEL FDVCFKQEDV DSLKKPNWFT DVSIDYVDEL IEHLWFPSYP NQANEILLLR 60 PSLVFLLAEA AISPEELKVA LPKKLMNCKY LFMPINDLDK HAAGSGGSHW SLMVASIPDG 120 QCYYYDSLSN GKTKDCRSAL ARVSDLFKKK FTIECMPVQQ QRNGYDCGAH VCAFTLELVR 180 RLLHSPMPTS SMWNLSTFQP DVTAIREQLS RCLDHIINSL GTRVSGDFDE DFPTGTVFFD 240 LESHLPLLDV ALPVLPKSSD SSETSHESSN SNLKKSSESG STNHHNNHES DKDLHHEGHH 300 HHHHHHHHHH SHDDDPSSPA EKKQNHVPSP SEKIQDHVPS PSEKKQDRVP SPSNNKEDHL 360 PLLSDEKLDK SAIDKIEPTP LPSVHMNSHI AKGELPKFHN STDNPFLTPP EELVSGDFPF 420 421 |
| Keyword | KW-0181--Complete proteome |
| Interpro | IPR003653--Peptidase_C48_C |
| PROSITE | PS50600--ULP_PROTEASE |
| Pfam | PF02902--Peptidase_C48 |
| Gene Ontology | GO:0005737--C:cytoplasm |