dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001407
Uniprot Accession O42954; MBX1_SCHPO;
Genbank Protein ID NP_595972.2;
Genbank Nucleotide ID NM_001021880.3;
Protein Name MADS-box transcription factor 1
Protein Synonyms/Alias
Gene Name mbx1
Gene Synonyms/Alias SPBC19G7.06;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Acts as a transcriptional activator with a role in the regulation of mitosis. Regulates septation and the periodic transcription of cdc15.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
372LSRSFTASPNQILREdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)
MDINPPPSTA PSSPRRSIQR ISDAKNKALT FNRRRLGLIK KAHELSVLCD AKVVVMIFDS 60
KNACHVYSSE EPEEQRDALL QKFLNKDFVT VDPLRNINPN IPSDESLHNW RPKDKRIASV 120
TTYSAQPSNN CSSATDSEND FQSFTIKSST TYHTTPTTAS ENKKIESITI PDHASVYNDL 180
PLSPTVKHSF VSPVSGDYSD SPLEPSSSSS FSVPPESLNP TLSFQHNDVP QTDNFIPFLT 240
PKRQAYGQSS SRADRSSVRR SQSFKNRRNG KPRISRLHTS HASIDGLTDF IQSPSSGYLD 300
PSSTPITPLD SAINQITPPF LPDNLGQENR GELYSHDNPT SMVYEHPKFD ELPNGFIDTH 360
ELNILSRSFT ASPNQILRES NMVNQDSFTD NPVDATWDAL IGTTQIDLDL DYERSSIPSS 420
TIPADQLKDG VPTNSVYRNN MVDHNLYPSL NIERNAP 458
Keyword

KW-0010--Activator
KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0498--Mitosis
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR002100--TF_MADSbox

PROSITE

PS00350--MADS_BOX_1
PS50066--MADS_BOX_2

Pfam

PF00319--SRF-TF

Gene Ontology

GO:0005829--C:cytosol
GO:0097221--C:M/G1 phase-specific MADS box-forkhead transcription factor complex
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000982--F:transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0051301--P:cell division
GO:0007067--P:mitotic nuclear division
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0006366--P:transcription from RNA polymerase II promoter