dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001399
Uniprot Accession O42924; EAF7_SCHPO; Q9USF9;
Genbank Protein ID NP_596770.1;
Genbank Nucleotide ID NM_001023791.2;
Protein Name Probable chromatin modification-related protein eaf7
Protein Synonyms/Alias
Gene Name eaf7
Gene Synonyms/Alias SPBC16A3.19;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Phosphorylation Sites
 dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
193RSSSRSISPVTEQPQdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
201PVTEQPQSPKIQPVIdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
230TLRKRSVSPSSQNTAcurated22817900
Sequence
(Fasta)		MSSRGTRSST AAEQKRQEDV NKESNMNDSV TEWSVLEETL LLKAICRGLR PVGIEKNFYM 60
IGILREIRDG CKRSTIKAQD VWNKLGTLYN LKEFEELEAP GNEEVKAKEK RIKSPDVKDF 120
KLPKDILKVK EKSEKPLETS QKVEIETVET KPGEPEVKQE TNLQKEKKES KVKLESKEEK 180
ISRNLRSSSR SISPVTEQPQ SPKIQPVIPE KKEKSEKKES SMTLRKRSVS PSSQNTARSP 240
KRMATEPIEP ASSPAASNQA IRRSSRSRRP PT 273
Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
Interpro

IPR012423--Eaf7/MRGBP
PROSITE
Pfam

PF07904--Eaf7
Gene Ontology

GO:0035267--C:NuA4 histone acetyltransferase complex
GO:0000790--C:nuclear chromatin
GO:0005634--C:nucleus
GO:0006338--P:chromatin remodeling
GO:0006281--P:DNA repair
GO:0016573--P:histone acetylation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0006351--P:transcription, DNA-templated