dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001396
Uniprot Accession O42916; ALE1_SCHPO; A9EDQ0;
Genbank Protein ID NP_596779.1;
Genbank Nucleotide ID NM_001023800.2;
Protein Name Lysophospholipid acyltransferase
Protein Synonyms/Alias
Gene Name ale1
Gene Synonyms/Alias lpt1;SPBC16A3.10;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Membrane-bound O-acyltransferase that mediates the incorporation of unsaturated acyl chains into the sn-2 position of phospholipids.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
490EQSMKSTSDTDMLNMdbPTM 3.0;UniProt18257517; 16381945; 23193290
Sequence
(Fasta)
MAYLIDIPFE YFSSFLGVHP DQLKLLFCFL SAYPFAGILK RLPSAPWIRN LFSISIGLFY 60
LIGVHHLYDG VLVLLFDALF TYFVAAFYRS SRMPWIIFIV ILGHTFSSHV IRYIYPSENT 120
DITASQMVLC MKLTAFAWSV YDGRLPSSEL SSYQKDRALR KIPNILYFLG YVFFFPSLLV 180
GPAFDYVDYE RFITLSMFKP LADPYEKQIT PHSLEPALGR CWRGLLWLIL FITGSSIYPL 240
KFLLTPKFAS SPILLKYGYV CITAFVARMK YYGAWELSDG ACILSGIGYN GLDSSKHPRW 300
DRVKNIDPIK FEFADNIKCA LEAWNMNTNK WLRNYVYLRV AKKGKRPGFK STLSTFTVSA 360
MWHGVSAGYY LTFVSAAFIQ TVAKYTRRHV RPFFLKPDME TPGPFKRVYD VIGMVATNLS 420
LSYLIISFLL LNLKESIHVW KELYFIVHIY ILIALAVFNS PIRSKLDNKI RSRVNSYKLK 480
SYEQSMKSTS DTDMLNMSVP KREDFENDE
Keyword

KW-0012--Acyltransferase
KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0444--Lipid biosynthesis
KW-0443--Lipid metabolism
KW-0472--Membrane
KW-0492--Microsome
KW-0594--Phospholipid biosynthesis
KW-1208--Phospholipid metabolism
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR004299--MBOAT_fam

PROSITE
Pfam

PF03062--MBOAT

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0003841--F:1-acylglycerol-3-phosphate O-acyltransferase activity
GO:0047184--F:1-acylglycerophosphocholine O-acyltransferase activity
GO:0046474--P:glycerophospholipid biosynthetic process
GO:0006646--P:phosphatidylethanolamine biosynthetic process