dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001393
Uniprot Accession O42906; GPN1_SCHPO;
Genbank Protein ID NP_595297.1;
Genbank Nucleotide ID NM_001021204.2;
Protein Name GPN-loop GTPase 1
Protein Synonyms/Alias
Gene Name SPBC119.15
Gene Synonyms/Alias
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
311EDVGLTVSDAEDEYNdbPTM 3.0;UniProt18257517; 16381945; 23193290
Sequence
(Fasta)
MTDKEKKPCA IIVVGMAGSG KTTFMQQLNA HLHSKNKPPY ILNLDPAVRN LPYEANIDIR 60
DTINYKEVMK QYNLGPNGGI MTSLNLFVTK FDQVLKILEK RAPTVDHILI DTPGQIEIFQ 120
WSASGSIICD TLASSWPTCI AYVVDTPRAT STSTWMSSML YACSMLYKAK LPLIIVYNKC 180
DVQDSEFAKK WMTDFEEFQQ AVTKDEGMSS EGATSGYMGS LVNSMSLMLE EFYRHLDFVS 240
CSSVTGEGMD DFLEAVKAKV KEYEEEYVPE MERMKEIQRQ TKERQKEAQL SKLMKDMHVS 300
KDKEDVGLTV SDAEDEYNGE LVDPDEDDGL TAEDREDMIK QYRVALGISD DISDEKLLEM 360
LTERMKQ 368
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0342--GTP-binding
KW-0378--Hydrolase
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR003593--AAA+_ATPase
IPR004130--Gpn
IPR030230--Gpn1/Npa3/XAB1
IPR027417--P-loop_NTPase

PROSITE
Pfam

PF03029--ATP_bind_1

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0016887--F:ATPase activity
GO:0005525--F:GTP binding
GO:1990114--P:RNA Polymerase II core complex assembly