dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001387
Uniprot Accession O42874; STU1_SCHPO;
Genbank Protein ID NP_594084.1;
Genbank Nucleotide ID NM_001019501.2;
Protein Name Protein peg1
Protein Synonyms/Alias
Gene Name peg1
Gene Synonyms/Alias SPAC3G9.12;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Microtubule binding protein that regulates the stability of dynamic microtubules. Required for mitotic spindle formation.
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
599IPSKRSVSATIKDESdbPTM 3.0;UniProt18257517; 16381945; 23193290
881TKETEMQSPIESKEGdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
1221MHKMENGSPINVDKNdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)
MADKDAQDFL KFLKSNASTD EKTRCLDTLR SFFNKNNIPN ADLGLFVECF RLALTTVNPL 60
LLRSSVACFE TFLRRLRAQY PTWLKFRVPM LKNLVIDHIA SRDLQKRVLN ILIDLWHFNP 120
SEIEKSLIHL STTSKSAETR IQCFKWFVLA HNAHLSFDVK SLRPALYINL ENANPSVREE 180
AKEVLLLIYK NLSTSAKMQF ITDVETTSGL RREILQSLVE ELSLISSSSE VIIVQNSASS 240
FQPAPFMTAV ATLYPGVELE NVKPLLANFS KQLEQDSASM LPAFEGRETE QNWSVRQDSV 300
LRLRQYLRGN ACIDYLPELL SVLKTLLPGI LLALLSLRTT LSSSAIQLIK EMAIILKSNI 360
DPFLELILPN LLKVCSVTKK LASQAANVTF AAILVNCGVL SRNLSFISLA AHDTNAQLRV 420
FSSNWIFMLI SLSPELKNLA SLQTNLKAFE KLICRGLADS NSQVREVYRK SFWKLSEYFP 480
SVQEELTNTL EPSVLKQLHL ANPNRQAASF NFSGPKRAPI RPLSNLRSFS KSQKEETSSN 540
SSNSSGTRRL GLPQRATPAS RERVLPYTRS QAFHSTSLPP SLPSGHSPSI AIPSKRSVSA 600
TIKDESKTFE LLKNIQRKYE LILSGSSVDL PSAEFLSSNL TDALYSGSSI CYSLIFSHSL 660
LDLTFQYVDI ASLLSQFLLC VYDPSNVGHS FALASFPYVK SHYDAHKYFP IVFDVLMNIS 720
NMAPHVKVFP FNTNQKRLII HGCLLWLKEI SDTKLNQLEN KPFFVTDKLR YYSSKILAMT 780
AKTKLTSKNW IPLSGLLFSL RAHDTFMFDG LLDRLNEESR TKLVSSWSKQ DAFDYSKSST 840
HQEHLSKNLP TLNTSSSSNS SQTDLLVPHG KGETKETEMQ SPIESKEGLL SKDTHIESPQ 900
GTSLEKENEE EGKNPVESNC SEESLDDHNI DQTLVNKKET LAQDSESLLQ KNNALNEKGF 960
ENQFGLSSSA AKVLNKDTLD HVSGPISNSV SSSFKDFTRT PFKEINGERE TGFELTSYVN 1020
ALSKKDDINV QKTENVDESV GLNAMFMDNV NQDSLNSVDQ SSGKDKLLLT SSTPNKPTTF 1080
FMPANEEILG SPAKDYDIHD QSYSVHELHS ENMRENVGQS SLIYNNRDYM NTPMNDFSLS 1140
FSEIKGGILE SPVESPMTGT ISPIDADESV LHDIPAYESL NKSESNKYQE QAYSTPLHHT 1200
LNVLPKNKWI LSRMHKMENG SPINVDKNLD DAVAALEAAV KELNDGSVNT KTLKFCIKVC 1260
KETPSMLYHS HGLLPAILHY IESNNSAMHI SDCLILLHEF LVQGYQGVDM HTYHNIICIL 1320
IEKAEKCKDE PVILAGIEDN ITLIAEIADL QGLYEFTQQR LQSLNTETGE KSAPLLLMLL 1380
SAILMRLKDL EFLETKDLLR HVVLKYIDHT NPEIRKATFN VCLAVNTIVN NVDETFSILG 1440
GLNEGQRLLF MHYLKMKSDE KN 1463
Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR024395--CLASP_N_dom

PROSITE
Pfam

PF12348--CLASP_N

Gene Ontology

GO:0005829--C:cytosol
GO:0005875--C:microtubule associated complex
GO:0015630--C:microtubule cytoskeleton
GO:0044732--C:mitotic spindle pole body
GO:0005635--C:nuclear envelope
GO:0005634--C:nucleus
GO:0005876--C:spindle microtubule
GO:0051233--C:spindle midzone
GO:0051301--P:cell division
GO:0007020--P:microtubule nucleation
GO:0090307--P:mitotic spindle assembly
GO:0032932--P:negative regulation of astral microtubule depolymerization
GO:0007026--P:negative regulation of microtubule depolymerization