dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001380
Uniprot Accession O42844; KCC2_SCHPO;
Genbank Protein ID NP_594436.1;
Genbank Nucleotide ID NM_001019865.2;
Protein Name Calcium/calmodulin-dependent protein kinase type II
Protein Synonyms/Alias
Gene Name cmk2
Gene Synonyms/Alias SPAC23A1.06c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Has a role in the regulation of G2/M transition during mitosis.
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
252VWNSKTATPCGTVGYdbPTM 3.0;UniProt18257517; 16381945; 23193290
393GEIDIPTTPIKSATHcurated22817900
436RLNHLGFSPEQLSKKdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)
MSILAGFKNL LKHSKSSKGR SNASKSVDVS VNRDVAAYTE LAAKNVNAGG DEEIRVANYP 60
GLEKYQLIEN LGDGAFSQVY KAYSIDRKEH VAVKVIRKYE MNKKQRQGVF KEVNIMRRVK 120
HKNVVNLFDF VETEDFYHLV MELAEGGELF HQIVNFTYFS ENLARHIIIQ VAEAVKHLHD 180
VCGIVHRDIK PENLLFQPIE YLPSQNYTPP SLEPNKLDEG MFLEGIGAGG IGRILIADFG 240
FSKVVWNSKT ATPCGTVGYA APEIVNDELY SKNVDMWAMG CVLHTMLCGF PPFFDENIKD 300
LASKVVNGEF EFLSPWWDDI SDSAKDLITH LLTVDPRERY DIHQFFQHPW IKGESKMPEN 360
FTYKPKLHGT PGGPKLSLPR SLVSKGEIDI PTTPIKSATH PLLSSYSEPK TPGVSSVHEA 420
MGVAYDIRRL NHLGFSPEQL SKKSMNTGSI KELILDEETT TDDDDYIISS FPLNDTLGSE 480
GKDPFSLNLK ESSLYSRRSA KRVN 505
Keyword

KW-0067--ATP-binding
KW-0112--Calmodulin-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR020636--Ca/CaM-dep_Ca-dep_prot_Kinase
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

Gene Ontology

GO:0000935--C:barrier septum
GO:0005938--C:cell cortex
GO:0051285--C:cell cortex of cell tip
GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004683--F:calmodulin-dependent protein kinase activity
GO:0004672--F:protein kinase activity
GO:0034599--P:cellular response to oxidative stress
GO:0010972--P:negative regulation of G2/M transition of mitotic cell cycle
GO:0046777--P:protein autophosphorylation
GO:0031098--P:stress-activated protein kinase signaling cascade