dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001375
Uniprot Accession O42668; TPR1_SCHPO; O42796;
Genbank Protein ID NP_594620.1;
Genbank Nucleotide ID NM_001020048.2;
Protein Name Tetratricopeptide repeat protein 1
Protein Synonyms/Alias
Gene Name tpr1
Gene Synonyms/Alias SPAC27D7.14c;SPAC637.02c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 Involved in promoting potassiumm ion uptake.
Phosphorylation Sites
 dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
834SVEHPPYSPTSIEQRcurated22817900
930KASEDDMSLSDDEEKdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
932SEDDMSLSDDEEKQSdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
959SKSKQESSDSGVSEDdbPTM 3.0;UniProt18257517; 16381945; 23193290
961SKQESSDSGVSEDDEdbPTM 3.0;UniProt18257517; 16381945; 23193290
964ESSDSGVSEDDEIPLdbPTM 3.0;UniProt18257517; 16381945; 23193290
998EYTFDQDSDAEGNQEdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
1034NKELNLFSEEDEE--dbPTM 3.0;SysPTM 2.018257517; 16381945; 23193290; 19366988
Sequence
(Fasta)		MEGFTLETHA SRIIEVPLLG QEDQSVEIDC SSLPSDATEL CEILVNEQAP REFWTKFAHE 60
YYIRGLREQA ILILKSGLET LKDSESLCIL NANIAAIYLS MAREAMLKKD TDLRDEQLRN 120
VRTYLEAANN IDSKSEINVL LHGIYRILLN PTDKESLENA ARCFDFVLQK SGGNILGFLG 180
KARILYAKGN YRSALKLYQR ALVSNPQFKP DPRIGIGLCF WNLDMKTDAL SAWTRVQQLD 240
PKNTVVDTYI GLYYYDLAFQ NVNNDSFVQN YGKALQHIQR AFKTRNNDPV ASSILERYVY 300
SKKNYEGCIK LAENVIQNSF SSSLIADGYY WMGRAYHQMG NNEKAMASYQ KAKAADDRHL 360
LSSVGIGQIQ ILQNDLTSAK LTFERIAEQN QSCFEALVVL GCLHASDSKP DLTKARMLLD 420
RAFNLVGSSK LPRVVDSDLY ITQARLWEKE DTKKSLGFLT RALDFLESAH MSVGPELLNN 480
IAVLQYHLGL IPEAHGNIIK AKSVLPDANP ELSLLLDYNL ARCEEELGNT SVASEAYVSI 540
LEKHPSFIDA RIRKCLLQLS NPNEETFKEI RHIMNADSQN LEVRAFFGWY LSKQKRRPVE 600
DPEVRHCSQT LRHWHDDIYS LVQLGNAYMR QAREFRVHND REKLKRQKLY IKAIQSYDQA 660
IKFDPKNAHA AQGIAIILAQ NRQFSKALLI LSKVREAIKD ATTLINIGNC LAELKQFSRA 720
IEVFETVYSS TGESDTYGVL SCLGRVWLQR GRESKNVDYL KESVRYATLA LEKNPENPSL 780
LFNVAFVQFQ LCELIRQKPE NSRTVEDLNF AMQQLDASIE TFTKLVSVEH PPYSPTSIEQ 840
RAKMAKNTTK RQLERAIQAQ IEYEKSVAAK LEDARIQREK EKARRLAEEE ALLKEKQERE 900
RQLQEERQKM QEEVLEWRKS QQKASEDDMS LSDDEEKQSG KKKKKDRKKR KSKSKQESSD 960
SGVSEDDEIP LSDARNKTKK RRVNRRVISE EYTFDQDSDA EGNQEEEVSR TIEEKQDNDI 1020
TDNQDDNKEL NLFSEEDEE
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0406--Ion transport
KW-0597--Phosphoprotein
KW-0630--Potassium
KW-0633--Potassium transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat
KW-0813--Transport
Interpro

IPR031101--Ctr9
IPR016137--RGS
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR013105--TPR_2
IPR019734--TPR_repeat
PROSITE

PS50005--TPR
PS50293--TPR_REGION
Pfam

PF07719--TPR_2
PF13181--TPR_8
Gene Ontology

GO:0016593--C:Cdc73/Paf1 complex
GO:0044732--C:mitotic spindle pole body
GO:0005634--C:nucleus
GO:0000993--F:RNA polymerase II core binding
GO:0016570--P:histone modification
GO:0006813--P:potassium ion transport
GO:0051569--P:regulation of histone H3-K4 methylation
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006368--P:transcription elongation from RNA polymerase II promoter