dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001370
Uniprot Accession O36027; WSP1_SCHPO;
Genbank Protein ID NP_594758.1;
Genbank Nucleotide ID NM_001020185.2;
Protein Name Wiskott-Aldrich syndrome protein homolog 1
Protein Synonyms/Alias
Gene Name wsp1
Gene Synonyms/Alias SPAC4F10.15c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Has a role in regulating actin assembly, so regulating polarized growth.
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
386LSSSRAVSNPPAPPPdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
410LPPLGNASRTSTPPVcurated22817900
Sequence
(Fasta)
MPPSSSITQE DKATIRKYIP KSTNKIIAAA VVKLYVAYPD PNKWNYTGLC GALVLSYDTT 60
AKCCWFKLVD VVNNSGIIWD QELYQNMDYR QDRTFFHSFE LDKCLAGFSF ANETDAQKFY 120
KKVLDKGCHP ESIENPVLSF ITRKGSSRHA PNNSNIQPPS AAPPVPGKEN YNAVGSKSPN 180
EPELLNSLDP SLIDSLMKMG ISQDQIAENA DFVKAYLNES AGTPTSTSAP PIPPSIPSSR 240
PPERVPSLSA PAPPPIPPPS NGTVSSPPNS PPRPIAPVSM NPAINSTSKP PLPPPSSRVS 300
AAALAANKKR PPPPPPPSRR NRGKPPIGNG SSNSSLPPPP PPPRSNAAGS IPLPPQGRSA 360
PPPPPPRSAP STGRQPPPLS SSRAVSNPPA PPPAIPGRSA PALPPLGNAS RTSTPPVPTP 420
PSLPPSAPPS LPPSAPPSLP MGAPAAPPLP PSAPIAPPLP AGMPAAPPLP PAAPAPPPAP 480
APAPAAPVAS IAELPQQDGR ANLMASIRAS GGMDLLKSRK VSASPSVAST KTSNPPVEAP 540
PSNNLMDALA SALNQRKTKV AQSDEEDEDD DEWD 575
Keyword

KW-0009--Actin-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR011993--PH/PTB_dom
IPR000697--WH1/EVH1_dom
IPR003124--WH2_dom
IPR028297--Wsp1/Las17_fungal

PROSITE

PS50229--WH1
PS51082--WH2

Pfam

PF00568--WH1

Gene Ontology

GO:0030479--C:actin cortical patch
GO:0005826--C:actomyosin contractile ring
GO:0051286--C:cell tip
GO:0043332--C:mating projection tip
GO:0000147--P:actin cortical patch assembly
GO:0044397--P:actin cortical patch internalization
GO:0030041--P:actin filament polymerization
GO:0045010--P:actin nucleation
GO:0006897--P:endocytosis
GO:0071963--P:establishment or maintenance of cell polarity regulating cell shape
GO:1903475--P:mitotic actomyosin contractile ring assembly
GO:1902404--P:mitotic actomyosin contractile ring contraction