dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001357
Uniprot Accession O35964; SH3G1_RAT;
Genbank Protein ID NP_112518.1;
Genbank Nucleotide ID NM_031239.2;
Protein Name Endophilin-A2
Protein Synonyms/Alias Endophilin-2;SH3 domain protein 2B;SH3 domain-containing GRB2-like protein 1;SH3p8;
Gene Name Sh3gl1
Gene Synonyms/Alias Sh3p8;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)		 Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
286SAPKITASSSFRSGDPhosphoSitePlus;curated22135298; 23984901
288PKITASSSFRSGDKPPhosphoSitePlus;UniProt22135298; 22673903
Sequence
(Fasta)		MSVAGLKKQF YKASQLVSEK VGGAEGTKLD DDFREMEKKV DITSKAVAEV LVRTIEYLQP 60
NPASRAKLTM LNTVSKIRGQ VKNPGYPQSE GLLGECMVRH GKELGGESNF GDALLDAGES 120
MKRLAEVKDS LDIEVKQNFI DPLQNLCDKD LKEIQHHLKK LEGRRLDFDY KKKRQGKIPD 180
EELRQALEKF EESKEVAETS MHNLLETDIE QVSQLSALVD AQLDYHRQAV QILEELADKL 240
KRRVREASSR PRREFKPRPQ EPFELGELEQ PNGGFPCASA PKITASSSFR SGDKPTRTPS 300
KSMPPLDQPS CKALYDFEPE NDGELGFREG DLITLTNQID ENWYEGMLHG QSGFFPLSYV 360
QVLVPLPQ 369
Keyword

KW-0002--3D-structure
KW-0965--Cell junction
KW-0966--Cell projection
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0254--Endocytosis
KW-0967--Endosome
KW-0446--Lipid-binding
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0728--SH3 domain
Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR001452--SH3_domain
PROSITE

PS51021--BAR
PS50002--SH3
Pfam

PF03114--BAR
PF00018--SH3_1
Gene Ontology

GO:0030054--C:cell junction
GO:0042995--C:cell projection
GO:0031901--C:early endosome membrane
GO:0002102--C:podosome
GO:0051020--F:GTPase binding
GO:0008289--F:lipid binding
GO:0019902--F:phosphatase binding
GO:0006897--P:endocytosis