| Tag |
Content |
| dbPAF ID |
dbPAF-0001329 |
| Uniprot Accession |
O35854; BCAT2_RAT;
|
| Genbank Protein ID |
NP_071795.1;
|
| Genbank Nucleotide ID |
NM_022400.1;
|
| Protein Name |
Branched-chain-amino-acid aminotransferase, mitochondrial |
| Protein Synonyms/Alias |
|
| Gene Name |
Bcat2 |
| Gene Synonyms/Alias |
Bcatm;Eca40; |
| Organism |
Rattus norvegicus(Rat) |
| NCBI Taxa ID |
10116 |
Functional Description
(View all) |
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids.Functional Description
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids. |
Phosphorylation Sites
|
dbPAF PTMs: 1 | Position | Peptides | Source | References ( PMIDs ) |
|---|
| 385 | KAIQYGTSAHDWMLR | PhosphoSitePlus | 22135298 |
|
Sequence
(Fasta) | MSAAILGQVW TRKLLPIPWR LCVPGRCVSS NFKAADLQVQ VTREPQKKPA PSQPLLFGKT 60
FTDHMLMVEW NSKTGWGPPR IQPFQNLTLH PACSGLHYSL QLFEGLKAYK GRDKQVRLFR 120
PWLNMDRMLR SARRLCLPDF DKQELLECIR QLIEVDKDWV PDGNGTSLYV RPVLIGNEPS 180
LGVGMVTQAL LFVILCPVGS YFPGDSMTPV SLLADPSFVR AWIGGVGDCK LGGNYGPTVA 240
VQQEAQKKGC EQVLWLYGPD HQLTEVGTMN IFVYWTHEDG ELELATPPLD GIILPGVVRQ 300
SLLDLARTWG EFRVAERKVT MKELKRALEE GRVREVFGSG TACQVCPVHQ ILYEGKQLHI 360
PTMENGPELI LRFQKELKAI QYGTSAHDWM LRV
394Fasta Sequence
>O35854|Bcat2|Rattus norvegicus(Rat)
MSAAILGQVWTRKLLPIPWRLCVPGRCVSSNFKAADLQVQVTREPQKKPAPSQPLLFGKTFTDHMLMVEWNSKTGWGPPRIQPFQNLTLHPACSGLHYSLQLFEGLKAYKGRDKQVRLFRPWLNMDRMLRSARRLCLPDFDKQELLECIRQLIEVDKDWVPDGNGTSLYVRPVLIGNEPSLGVGMVTQALLFVILCPVGSYFPGDSMTPVSLLADPSFVRAWIGGVGDCKLGGNYGPTVAVQQEAQKKGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGELELATPPLDGIILPGVVRQSLLDLARTWGEFRVAERKVTMKELKRALEEGRVREVFGSGTACQVCPVHQILYEGKQLHIPTMENGPELILRFQKELKAIQYGTSAHDWMLRV
|
| Keyword |
KW-0007--Acetylation
KW-0028--Amino-acid biosynthesis
KW-0032--Aminotransferase
KW-0100--Branched-chain amino acid biosynthesis
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0496--Mitochondrion
KW-0663--Pyridoxal phosphate
KW-1185--Reference proteome
KW-0808--Transferase
KW-0809--Transit peptide
|
| Interpro |
IPR001544--Aminotrans_IV
IPR018300--Aminotrans_IV_CS
IPR005786--B_amino_transII
|
| PROSITE |
PS00770--AA_TRANSFER_CLASS_4
|
| Pfam |
PF01063--Aminotran_4
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0005739--C:mitochondrion
GO:0005634--C:nucleus
GO:0004084--F:branched-chain-amino-acid transaminase activity
GO:0052656--F:L-isoleucine transaminase activity
GO:0052654--F:L-leucine transaminase activity
GO:0052655--F:L-valine transaminase activity
GO:0009083--P:branched-chain amino acid catabolic process
GO:0009081--P:branched-chain amino acid metabolic process
GO:0006550--P:isoleucine catabolic process
GO:0007595--P:lactation
GO:0009098--P:leucine biosynthetic process
|
