dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001327
Uniprot Accession O35832; CKD18_RAT;
Genbank Protein ID NP_001093976.1; XP_006249813.1; XP_006249814.1; XP_006249815.1; XP_008767663.1;
Genbank Nucleotide ID NM_001100506.1; XM_006249751.2; XM_006249752.2; XM_006249753.2; XM_008769441.1;
Protein Name Cyclin-dependent kinase 18
Protein Synonyms/Alias Cell division protein kinase 18;PCTAIRE-motif protein kinase 3;Serine/threonine-protein kinase PCTAIRE-3;
Gene Name Cdk18
Gene Synonyms/Alias Pctaire3;Pctk3;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)		 May play a role in signal transduction cascades in terminally differentiated cells.
Phosphorylation Sites
 dbPAF PTMs: 9
PositionPeptidesSourceReferences ( PMIDs )
12KNFKRRLSLSVPRPEPhosphoSitePlus22135298
51RDEPGQLSPGVQYQQdbPTM 3.0;PhosphoSitePlus;UniProt;curated16641100; 17683130; 16381945; 23193290; 22135298; 22673903;
66RQNQRRFSMEDLNKRdbPTM 3.0;PhosphoSitePlus;UniProt;curated16641100; 16381945; 23193290; 22135298; 22673903; 22817900;
75EDLNKRLSLPMDIRLPhosphoSitePlus;curated22135298; 23984901
109TRMSRRASLSDIGFGdbPTM 3.0;PhosphoSitePlus;curated16641100; 16381945; 23193290; 22135298; 22817900; 23984901
111MSRRASLSDIGFGKLdbPTM 3.0;PhosphoSitePlus;curated16641100; 16381945; 23193290; 22135298; 22817900
132DKLGEGTYATVFKGRPhosphoSitePlus22135298
417HQLDDTASIFSLKEIPhosphoSitePlus;UniProt22135298; 22673903
420DDTASIFSLKEIQLQPhosphoSitePlus;UniProt22135298; 22673903
Sequence
(Fasta)		MNKMKNFKRR LSLSVPRPET IEESLTEFTE QFNQLHTQRN EDGRDEPGQL SPGVQYQQRQ 60
NQRRFSMEDL NKRLSLPMDI RLPQEFLQKL QLENPGLPKP LTRMSRRASL SDIGFGKLET 120
YVKLDKLGEG TYATVFKGRS KLTENLVALK EIRLEHEEGA PCTAIREVSL LKDLKHANIV 180
TLHDLIHTDR SLTLVFEYLD SDLKQYLDHC GNLMNMHNVK IFMFQLLRGL AYCHRRKILH 240
RDLKPQNLLI NERGELKLAD FGLARAKSVP TKTYSNEVVT LWYRPPDVLL GSTEYSTPID 300
MWGVGCILYE MATGKPLFPG STVKEELHLI FRLLGTPTEE SWPGVTSISE FRAYNFPRYL 360
PQPLLSHAPR LDTEGINLLT SLLLYESKSR MSAEAALSHP YFQSLGERVH QLDDTASIFS 420
LKEIQLQKDP GYRGLAFQHP GRGKSRRQSI F 452
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
Pfam

PF00069--Pkinase
Gene Ontology

GO:0005524--F:ATP binding
GO:0004693--F:cyclin-dependent protein serine/threonine kinase activity