dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001326
Uniprot Accession O35831; CDK17_RAT;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Cyclin-dependent kinase 17
Protein Synonyms/Alias Cell division protein kinase 17;PCTAIRE-motif protein kinase 2;Serine/threonine-protein kinase PCTAIRE-2;
Gene Name Cdk17
Gene Synonyms/Alias Pctaire2;Pctk2;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)		 May play a role in terminally differentiated neurons. Has a Ser/Thr-phosphorylating activity for histone H1.
Phosphorylation Sites
 dbPAF PTMs: 10
PositionPeptidesSourceReferences ( PMIDs )
9KKFKRRLSLTLRGSQcurated25532521; 23984901
92MAMPRNGSRLDIVHEcurated23984901
137NRIHRRISMEDLNKRdbPTM 3.0;PhosphoSitePlus;UniProt;curated16641100; 16381945; 23193290; 22135298; 22673903; 22817900;
146EDLNKRLSLPADIRIPhosphoSitePlus22135298
165LEKLQISSPPFDQPMPhosphoSitePlus;curated22135298; 22276854
180SRRSRRASLSEIGFGPhosphoSitePlus;UniProt;curated22135298; 22673903; 25532521
192GFGKMETYIKLEKLGPhosphoSitePlus22135298
203EKLGEGTYATVYKGRPhosphoSitePlus22135298
207EGTYATVYKGRSKLTPhosphoSitePlus22135298
472EEAMKHVYFRSLGPRPhosphoSitePlus22135298
Sequence
(Fasta)		MKKFKRRLSL TLRGSQTIDE SLSELAEQMT IEESSSKDNE PIVKNGRPPT SHSMHSFLHQ 60
YTGSFKKPPL RRPHSVIGGS LGSFMAMPRN GSRLDIVHEN LKMGSDGESD QASGTSSDEV 120
QSPTGVCLRN RIHRRISMED LNKRLSLPAD IRIPDGYLEK LQISSPPFDQ PMSRRSRRAS 180
LSEIGFGKME TYIKLEKLGE GTYATVYKGR SKLTENLVAL KEIRLEHEEG APCTAIREVS 240
LLKDLKHANI VTLHDIVHTD KSLTLVFEYL DKDLKQYMDD CGSIMSMHNV KLFLYQILRG 300
LAYCHRRKVL HRDLKPQNLL INERGELKLA DFGLARAKSV PTKTYSNEVV TLWYRPPDVL 360
LGSSEYSTQI DMWGVGCIFF EMASGRPLFP GSTVEDELHL IFRLLGTPSQ ETWPGVSSND 420
EFKNYNFPKY KPQPLINHAP RLDSEGIELI TKFLQYESKK RAPAEEAMKH VYFRSLGPRI 480
HALPESVSIF SLKEIQLQKD PGFRNSSYPE TGVFVINHFT CRS 524
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
Pfam

PF00069--Pkinase
Gene Ontology

GO:0005524--F:ATP binding
GO:0004693--F:cyclin-dependent protein serine/threonine kinase activity