| Tag |
Content |
| dbPAF ID |
dbPAF-0001321 |
| Uniprot Accession |
O35820; DNPH1_RAT;
|
| Genbank Protein ID |
NP_598209.1;
|
| Genbank Nucleotide ID |
NM_133525.1;
|
| Protein Name |
2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
| Protein Synonyms/Alias |
Deoxyribonucleoside 5'-monophosphate N-glycosidase;c-Myc-responsive protein Rcl; |
| Gene Name |
Dnph1 |
| Gene Synonyms/Alias |
Rcl; |
| Organism |
Rattus norvegicus(Rat) |
| NCBI Taxa ID |
10116 |
Functional Description
(View all) |
Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.Functional Description
Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases. |
Phosphorylation Sites
|
dbPAF PTMs: 2 |
Sequence
(Fasta) | MAASGEQAPC SVYFCGSIRG GREDQALYAR IVSRLRRYGK VLTEHVADAE LEPLGEEAAG 60
GDQFIHEQDL NWLQQADVVV AEVTQPSLGV GYELGRAVAL GKPILCLFRP QSGRVLSAMI 120
RGAADGSRFQ VWDYAEGEVE TMLDRYFEAY LPQKTASSSH PSA
164Fasta Sequence
>O35820|Dnph1|Rattus norvegicus(Rat)
MAASGEQAPCSVYFCGSIRGGREDQALYARIVSRLRRYGKVLTEHVADAELEPLGEEAAGGDQFIHEQDLNWLQQADVVVAEVTQPSLGVGYELGRAVALGKPILCLFRPQSGRVLSAMIRGAADGSRFQVWDYAEGEVETMLDRYFEAYLPQKTASSSHPSA
|
| Keyword |
KW-0002--3D-structure
KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0326--Glycosidase
KW-0378--Hydrolase
KW-0546--Nucleotide metabolism
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
|
| Interpro |
IPR028607--DNPH1
IPR007710--Nucleoside_deoxyribTrfase
|
| PROSITE |
|
| Pfam |
PF05014--Nuc_deoxyrib_tr
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0070694--F:deoxyribonucleoside 5'-monophosphate N-glycosidase activity
GO:0050144--F:nucleoside deoxyribosyltransferase activity
GO:0042803--F:protein homodimerization activity
GO:0009159--P:deoxyribonucleoside monophosphate catabolic process
GO:0030855--P:epithelial cell differentiation
GO:0009116--P:nucleoside metabolic process
GO:0009117--P:nucleotide metabolic process
GO:0030307--P:positive regulation of cell growth
|
