Tag |
Content |
dbPAF ID |
dbPAF-0001312 |
Uniprot Accession |
O35783; CALU_RAT; |
Genbank Protein ID |
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Genbank Nucleotide ID |
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Protein Name |
Calumenin |
Protein Synonyms/Alias |
CBP-50;Crocalbin; |
Gene Name |
Calu |
Gene Synonyms/Alias |
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Organism |
Rattus norvegicus(Rat) |
NCBI Taxa ID |
10116 |
Functional Description (View all) |
Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity (By similarity).Functional Description
Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity (By similarity).
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Phosphorylation Sites
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dbPAF PTMs: 4 |
Sequence (Fasta) | MDLRQFLMCL SLCTAFALSK PTEKKDRVHH EPQLSDKVHN DAQNFDYDHD AFLGAEEAKS 60 FGQLTPEESK EKLGMIVDKI DTDKDGFVTE GELKSRIKHA QKKYIYDNVE NQWQEFDMNQ 120 DGLISWDEYR NVTYGTYLDD PDPDDGFNYK PIMVRDERRF KMADQDGDLI ATKEEFTAFL 180 HPEEYDYMKD IVLQETMEDI DQNADGFIDL EEYIGDMYSH DGNADEPQWV KTEREQFVEF 240 RDKNRDGKMD KEETKDWILP SDYDHAEAEA RHLVYESDQD KDGKLTKEEI VDKYDLFVGS 300 QATDFGEALV RHDEF
316Fasta Sequence
>O35783|Calu|Rattus norvegicus(Rat) MDLRQFLMCLSLCTAFALSKPTEKKDRVHHEPQLSDKVHNDAQNFDYDHDAFLGAEEAKSFGQLTPEESKEKLGMIVDKIDTDKDGFVTEGELKSRIKHAQKKYIYDNVENQWQEFDMNQDGLISWDEYRNVTYGTYLDDPDPDDGFNYKPIMVRDERRFKMADQDGDLIATKEEFTAFLHPEEYDYMKDIVLQETMEDIDQNADGFIDLEEYIGDMYSHDGNADEPQWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQDKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDEF
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Keyword |
KW-0106--Calcium KW-0181--Complete proteome KW-0903--Direct protein sequencing KW-0256--Endoplasmic reticulum KW-0325--Glycoprotein KW-0479--Metal-binding KW-0597--Phosphoprotein KW-1185--Reference proteome KW-0677--Repeat KW-0703--Sarcoplasmic reticulum KW-0964--Secreted KW-0732--Signal
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Interpro |
IPR011992--EF-hand-dom_pair IPR018247--EF_Hand_1_Ca_BS IPR002048--EF_hand_dom
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PROSITE |
PS00018--EF_HAND_1 PS50222--EF_HAND_2
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Pfam |
PF13202--EF-hand_5 PF13499--EF-hand_7
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Gene Ontology |
GO:0005788--C:endoplasmic reticulum lumen GO:0005576--C:extracellular region GO:0043231--C:intracellular membrane-bounded organelle GO:0042470--C:melanosome GO:0033018--C:sarcoplasmic reticulum lumen GO:0005509--F:calcium ion binding GO:0019899--F:enzyme binding GO:0004857--F:enzyme inhibitor activity GO:0043086--P:negative regulation of catalytic activity GO:0014012--P:peripheral nervous system axon regeneration GO:0014070--P:response to organic cyclic compound
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