dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001308
Uniprot Accession O35764; NPTXR_RAT;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Neuronal pentraxin receptor
Protein Synonyms/Alias
Gene Name Nptxr
Gene Synonyms/Alias Npr;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
254RAALSHGSHQQRQEVcurated23984901
Sequence
(Fasta)
MKFLAVLLAA GMLAFLGAVI CIIASVPLAA SPARALPGGT DNASAASAAG APGPQRSLSA 60
LQGAGGSAGP SVLPGEPAAS VFPPPPGPLL SRFLCTPLAA ACPSGAEQGD AAGERAELLL 120
LQSTAEQLRQ TALQQEARIR ADRDTIRELT GKLGRCESGL PRGLQDAGPR RDTMADGAWD 180
SPALLVELEN AVRALRDRIE RIEQELPARG NLSSSAPAPA VPTALHSKMD ELEGQLLAKV 240
LALEKERAAL SHGSHQQRQE VEKELDALQG RVAELEHGSS AYSPPDAFKV SIPIRNNYMY 300
ARVRKAVPEL YAFTACMWLR SRSGGSGQGT PFSYSVPGQA NEIVLLEAGL EPMELLINDK 360
VAQLPLSLKD SNWHHICIAW TTRDGLWSAY QDGELRGSGE NLAAWHPIKP HGILILGQEQ 420
DTLGGRFDAT QAFVGDIAQF NLWDHALTPA QVLGIANCTG PLMGNVLPWE DKLVEAFGGA 480
KKAAFDVCKR RAKA 495
Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0325--Glycoprotein
KW-0472--Membrane
KW-0479--Metal-binding
KW-0675--Receptor
KW-1185--Reference proteome
KW-0735--Signal-anchor
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0832--Ubl conjugation

Interpro

IPR013320--ConA-like_dom
IPR001759--Pentaxin-related

PROSITE
Pfam

PF00354--Pentaxin

Gene Ontology

GO:0005615--C:extracellular space
GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0046872--F:metal ion binding
GO:0008029--F:pentraxin receptor activity
GO:0032403--F:protein complex binding
GO:0042542--P:response to hydrogen peroxide
GO:0007165--P:signal transduction