dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001306
Uniprot Accession O35760; IDI1_RAT; Q5FVT3;
Genbank Protein ID NP_445991.2;
Genbank Nucleotide ID NM_053539.2;
Protein Name Isopentenyl-diphosphate Delta-isomerase 1
Protein Synonyms/Alias Isopentenyl pyrophosphate isomerase 1;IPP isomerase 1;IPPI1;
Gene Name Idi1
Gene Synonyms/Alias
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
55GLIHRAFSVFLFNTEcurated23984901
216WDNLNHLSPFVDHEKcurated23984901
Sequence
(Fasta)
MPEINASNLD EKQVQLLAEM CILIDENDNK IGADTKKNCH LNENIDKGLI HRAFSVFLFN 60
TENKLLLQQR SDAKITFPGC FTNSCCSHPL NNPGELEEND AMGVKRAAQR RLKAELGIPL 120
EEVDLNEMNY LTRIYYKAQS DGIWGEHEID YILFLRKNVT LNPDPNEIKS YCYVSKEELK 180
EILKKEARGE IKLTPWFKII ADAFLFKWWD NLNHLSPFVD HEKIHRM 228
Keyword

KW-0007--Acetylation
KW-0152--Cholesterol biosynthesis
KW-0153--Cholesterol metabolism
KW-0181--Complete proteome
KW-0413--Isomerase
KW-0414--Isoprene biosynthesis
KW-0444--Lipid biosynthesis
KW-0443--Lipid metabolism
KW-0460--Magnesium
KW-0479--Metal-binding
KW-0576--Peroxisome
KW-1185--Reference proteome
KW-0752--Steroid biosynthesis
KW-0753--Steroid metabolism
KW-0756--Sterol biosynthesis
KW-1207--Sterol metabolism

Interpro

IPR011876--IsopentenylPP_isomerase_typ1
IPR000086--NUDIX_hydrolase_dom
IPR015797--NUDIX_hydrolase_dom-like

PROSITE

PS51462--NUDIX

Pfam

PF00293--NUDIX

Gene Ontology

GO:0005777--C:peroxisome
GO:0016787--F:hydrolase activity
GO:0004452--F:isopentenyl-diphosphate delta-isomerase activity
GO:0000287--F:magnesium ion binding
GO:0030145--F:manganese ion binding
GO:0006695--P:cholesterol biosynthetic process
GO:0050992--P:dimethylallyl diphosphate biosynthetic process
GO:0008299--P:isoprenoid biosynthetic process