Tag |
Content |
dbPAF ID |
dbPAF-0001306 |
Uniprot Accession |
O35760; IDI1_RAT; Q5FVT3; |
Genbank Protein ID |
NP_445991.2; |
Genbank Nucleotide ID |
NM_053539.2; |
Protein Name |
Isopentenyl-diphosphate Delta-isomerase 1 |
Protein Synonyms/Alias |
Isopentenyl pyrophosphate isomerase 1;IPP isomerase 1;IPPI1; |
Gene Name |
Idi1 |
Gene Synonyms/Alias |
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Organism |
Rattus norvegicus(Rat) |
NCBI Taxa ID |
10116 |
Functional Description (View all) |
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).Functional Description
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
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Phosphorylation Sites
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dbPAF PTMs: 2 Position | Peptides | Source | References ( PMIDs ) |
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55 | GLIHRAFSVFLFNTE | curated | 23984901 | 216 | WDNLNHLSPFVDHEK | curated | 23984901 |
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Sequence (Fasta) | MPEINASNLD EKQVQLLAEM CILIDENDNK IGADTKKNCH LNENIDKGLI HRAFSVFLFN 60 TENKLLLQQR SDAKITFPGC FTNSCCSHPL NNPGELEEND AMGVKRAAQR RLKAELGIPL 120 EEVDLNEMNY LTRIYYKAQS DGIWGEHEID YILFLRKNVT LNPDPNEIKS YCYVSKEELK 180 EILKKEARGE IKLTPWFKII ADAFLFKWWD NLNHLSPFVD HEKIHRM
228Fasta Sequence
>O35760|Idi1|Rattus norvegicus(Rat) MPEINASNLDEKQVQLLAEMCILIDENDNKIGADTKKNCHLNENIDKGLIHRAFSVFLFNTENKLLLQQRSDAKITFPGCFTNSCCSHPLNNPGELEENDAMGVKRAAQRRLKAELGIPLEEVDLNEMNYLTRIYYKAQSDGIWGEHEIDYILFLRKNVTLNPDPNEIKSYCYVSKEELKEILKKEARGEIKLTPWFKIIADAFLFKWWDNLNHLSPFVDHEKIHRM
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Keyword |
KW-0007--Acetylation KW-0152--Cholesterol biosynthesis KW-0153--Cholesterol metabolism KW-0181--Complete proteome KW-0413--Isomerase KW-0414--Isoprene biosynthesis KW-0444--Lipid biosynthesis KW-0443--Lipid metabolism KW-0460--Magnesium KW-0479--Metal-binding KW-0576--Peroxisome KW-1185--Reference proteome KW-0752--Steroid biosynthesis KW-0753--Steroid metabolism KW-0756--Sterol biosynthesis KW-1207--Sterol metabolism
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Interpro |
IPR011876--IsopentenylPP_isomerase_typ1 IPR000086--NUDIX_hydrolase_dom IPR015797--NUDIX_hydrolase_dom-like
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PROSITE |
PS51462--NUDIX
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Pfam |
PF00293--NUDIX
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Gene Ontology |
GO:0005777--C:peroxisome GO:0016787--F:hydrolase activity GO:0004452--F:isopentenyl-diphosphate delta-isomerase activity GO:0000287--F:magnesium ion binding GO:0030145--F:manganese ion binding GO:0006695--P:cholesterol biosynthetic process GO:0050992--P:dimethylallyl diphosphate biosynthetic process GO:0008299--P:isoprenoid biosynthetic process
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