dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001199
Uniprot Accession O35353; GBB4_RAT; Q4V8I8; Q6Q8B2;
Genbank Protein ID NP_001013932.1;
Genbank Nucleotide ID NM_001013910.2;
Protein Name Guanine nucleotide-binding protein subunit beta-4
Protein Synonyms/Alias Transducin beta chain 4;
Gene Name Gnb4
Gene Synonyms/Alias
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)		 Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Phosphorylation Sites
 dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
2------MSELEQLRQPhosphoSitePlus;curated22135298; 23984901
111AYAPSGNYVACGGLDPhosphoSitePlus22135298
239VSFFPSGYAFATGSDPhosphoSitePlus22135298
Sequence
(Fasta)		MSELEQLRQE AEQLRNQIQD ARKACNDATL VQITSNMDSV GRIQMRTRRT LRGHLAKIYA 60
MHWGYDSRLL VSASQDGKLI IWDSYTTNKM HAIPLRSSWV MTCAYAPSGN YVACGGLDNI 120
CSIYNLKTRE GNVRVSRELP GHTGYLSCCR FLDDGQIITS SGDTTCALWD IETGQQTTTF 180
TGHSGDVMSL SLSPDLKTFV SGACDASSKL WDIRDGMCRQ SFTGHISDIN AVSFFPSGYA 240
FATGSDDATC RLFDLRADQE LLLYSHDNII CGITSVAFSK SGRLLLAGYD DFNCSVWDAL 300
KGGRAGVLAG HDNRVSCLGV TDDGMAVATG SWDSFLRIWN 341
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0807--Transducer
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
Gene Ontology

GO:0044297--C:cell body
GO:0004871--F:signal transducer activity