dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001190
Uniprot Accession O35314; SCG1_RAT; A1A5N9; Q9QVG8; Q9QVH1;
Genbank Protein ID NP_036658.2;
Genbank Nucleotide ID NM_012526.2;
Protein Name Secretogranin-1
Protein Synonyms/Alias Chromogranin-B;CgB;Glucagonoma peptide;Secretogranin-I;SgI;
Gene Name Chgb
Gene Synonyms/Alias
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)		 Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.
Phosphorylation Sites
 dbPAF PTMs: 36 (View all)
PositionPeptidesSourceReferences ( PMIDs )
93LRDPSDASVGRWASSPhosphoSitePlus;UniProt22135298; 22673903
100SVGRWASSREETGAPPhosphoSitePlus22135298
129WTGGGGHSREAVDDQPhosphoSitePlus;UniProt;curated22135298; 22673903; 22276854
147HPSNQQVSKEAKIRHPhosphoSitePlus;UniProt;curated22135298; 22673903; 22276854
155KEAKIRHSEERGGKEPhosphoSitePlus22135298
171EEEEGKIYPKGEHRGPhosphoSitePlus22135298
190EKKHTEESGEKHNAFPhosphoSitePlus;UniProt22135298; 22673903
233THSREQSSQESGEETPhosphoSitePlus22135298
236REQSSQESGEETRRQPhosphoSitePlus22135298
255ELPDQDQSEEESEEGPhosphoSitePlus;UniProt;curated22135298; 22673903; 22276854
259QDQSEEESEEGEEGEPhosphoSitePlus;UniProt;curated22135298; 22673903; 22276854
271EGEEGATSEVTKRRPcurated22276854
291RSQSNKPSYEGRRPLPhosphoSitePlus22135298
292SQSNKPSYEGRRPLSPhosphoSitePlus22135298
299YEGRRPLSEERKHAAPhosphoSitePlus22135298
333HLAHYRASEEEPDYGPhosphoSitePlus;UniProt22135298; 22673903
339ASEEEPDYGEELRSYPhosphoSitePlus22135298
357QAPQGLQYQGRGSEEPhosphoSitePlus22135298
362LQYQGRGSEEVRAPSPhosphoSitePlus22135298
372VRAPSPRSEESQEKEPhosphoSitePlus22135298
Sequence
(Fasta)		MQRAMLLGLL GAAALAAVIS APVDNRDHNE EMVTRCIIEV LSNALSKSSA PTITPECRQV 60
LRKSGKEVKG EEKGENENSK FEVRLLRDPS DASVGRWASS REETGAPVED SPGQAKVDNE 120
EWTGGGGHSR EAVDDQESLH PSNQQVSKEA KIRHSEERGG KEEEEEEGKI YPKGEHRGDA 180
GEEKKHTEES GEKHNAFSNK RSEASAKKKE ESVARAEAHF VELEKTHSRE QSSQESGEET 240
RRQEKPQELP DQDQSEEESE EGEEGEEGAT SEVTKRRPRH HHWRSQSNKP SYEGRRPLSE 300
ERKHAAGESK DANVATANLG EKRGHHLAHY RASEEEPDYG EELRSYPGFQ APQGLQYQGR 360
GSEEVRAPSP RSEESQEKEY KRNHPDSELE STANRHSEET EEERSYEGAK GRQHRGRGRE 420
PGAYPALDSR QEKRLLDEGH DPVHESPVDT AKRYPQSKWQ EQEKNYLNYD EEGDQGRWWQ 480
QEEQLEPEES REEVSFPDRQ YAPYPTTEKR KRLGALFNPY FDPLQWKNSD FEKKGNPDDS 540
FLDDDGEDGN GVTMTEKNFF PEYNYDWWEK RPFSEDVNWG YEKRSFARAP HLDLKRQYDD 600
GVAELDQLLH YRKKAAEFPD FYDSEEQMGP HQEAEDEKDR ADQRVLTEEE KKELENLAAM 660
DLELQKIAEK FSQRG 676
Keyword

KW-0027--Amidation
KW-0165--Cleavage on pair of basic residues
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-1015--Disulfide bond
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0964--Secreted
KW-0732--Signal
KW-0765--Sulfation
Interpro

IPR001819--Chromogranin_AB
IPR018054--Chromogranin_CS
IPR001990--Granin
PROSITE

PS00422--GRANINS_1
PS00423--GRANINS_2
Pfam

PF01271--Granin
Gene Ontology

GO:0005576--C:extracellular region
GO:0030141--C:secretory granule