dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001178
Uniprot Accession O35264; PA1B2_RAT;
Genbank Protein ID NP_071782.1; XP_006243019.1; XP_006243020.1; XP_008764394.1;
Genbank Nucleotide ID NM_022387.3; XM_006242957.2; XM_006242958.2; XM_008766172.1;
Protein Name Platelet-activating factor acetylhydrolase IB subunit beta
Protein Synonyms/Alias PAF acetylhydrolase 30 kDa subunit;PAF-AH 30 kDa subunit;PAF-AH subunit beta;PAFAH subunit beta;Platelet-activating factor acetylhydrolase alpha 2 subunit;PAF-AH alpha 2;
Gene Name Pafah1b2
Gene Synonyms/Alias Pafahb;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)		 Inactivates PAF by removing the acetyl group at the sn-2 position. This is a catalytic subunit.
Phosphorylation Sites
 dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
2------MSQGDSNPAPhosphoSitePlus;UniProt;curated22135298; 22673903; 23984901
64EIWRELFSPLHALNFUniProt;curated22673903; 23984901
220IMQLLEETPEEKQTTPhosphoSitePlus;UniProt;curated22135298; 22673903; 23984901
Sequence
(Fasta)		MSQGDSNPAA IPHAAEDIQG DDRWMSQHNR FVLDCKDKEP DVLFVGDSMV QLMQQYEIWR 60
ELFSPLHALN FGIGGDTTRH VLWRLKNGEL ENIKPKVIVV WVGTNNHENT AEEVAGGIEA 120
IVQLINTRQP QAKIIVLGLL PRGEKPNPLR QKNAKVNQLL KVSLPKLANV QLLDIDGGFV 180
HSDGAISCHD MFDFLHLTGG GYAKICKPLH ELIMQLLEET PEEKQTTIA
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR013830--SGNH_hydro
PROSITE
Pfam

PF13472--Lipase_GDSL_2
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005730--C:nucleolus
GO:0005886--C:plasma membrane
GO:0003847--F:1-alkyl-2-acetylglycerophosphocholine esterase activity
GO:0047179--F:platelet-activating factor acetyltransferase activity
GO:0046982--F:protein heterodimerization activity
GO:0042803--F:protein homodimerization activity
GO:0007420--P:brain development
GO:0016042--P:lipid catabolic process
GO:0016239--P:positive regulation of macroautophagy
GO:0007283--P:spermatogenesis