dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001177
Uniprot Accession O35263; PA1B3_RAT;
Genbank Protein ID NP_446106.1; XP_006228427.1;
Genbank Nucleotide ID NM_053654.2; XM_006228365.2;
Protein Name Platelet-activating factor acetylhydrolase IB subunit gamma
Protein Synonyms/Alias PAF acetylhydrolase 29 kDa subunit;PAF-AH 29 kDa subunit;PAF-AH subunit gamma;PAFAH subunit gamma;Platelet-activating factor acetylhydrolase alpha 1 subunit;PAF-AH alpha 1;
Gene Name Pafah1b3
Gene Synonyms/Alias Pafahg;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)		 Inactivates paf by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Plays an important role during the development of brain.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
64EIWRELFSPLHALNFPhosphoSitePlus22135298
Sequence
(Fasta)		MSGEGENPAS KPTPVQDVQG DGRWMSLHHR FVADSKDKEP EVVFIGDSLV QLMHQCEIWR 60
ELFSPLHALN FGIGGDSTQH VLWRLENGEL EHIRPKIVVV WVGTNNHSHT AEQVTGGIKA 120
IVQLVNKLQP QARVVVLGLL PRGQHPNPLR EKNRQVNELV RAALAGYPRA HFLDADPGFV 180
HSDGTISHHD MYDYLHLSRL GYTPVCRALH SLLLRLLAQD QGQGIPLPET AP 233
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-1185--Reference proteome
Interpro

IPR013830--SGNH_hydro
PROSITE
Pfam

PF13472--Lipase_GDSL_2
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0016020--C:membrane
GO:0003847--F:1-alkyl-2-acetylglycerophosphocholine esterase activity
GO:0047179--F:platelet-activating factor acetyltransferase activity
GO:0046982--F:protein heterodimerization activity
GO:0007420--P:brain development
GO:0016042--P:lipid catabolic process
GO:0007283--P:spermatogenesis