dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001174
Uniprot Accession O35254; GORS1_RAT;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Golgi reassembly-stacking protein 1
Protein Synonyms/Alias Golgi peripheral membrane protein p65;Golgi reassembly-stacking protein of 65 kDa;GRASP65;
Gene Name Gorasp1
Gene Synonyms/Alias Grasp65;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)		 Stacking factor involved in the postmitotic assembly of Golgi stacks from mitotic Golgi fragments. Key structural protein required for the maintenance of the Golgi apparatus integrity: its caspase-mediated cleavage is required for fragmentation of the Golgi during apoptosis. Also mediates, via its interaction with GOLGA2/GM130, the docking of transport vesicles with the Golgi membranes.
Phosphorylation Sites
 dbPAF PTMs: 11
PositionPeptidesSourceReferences ( PMIDs )
214SQYKKPPSASSPGTPcurated23712012; 21630457
216YKKPPSASSPGTPAKdbPTM 3.0;Phospho.ELM 9.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated16396499; 16381945; 23193290; 22135298; 19366988; 22673903;
217KKPPSASSPGTPAKTcurated23712012; 21630457
220PSASSPGTPAKTPQPdbPTM 3.0;Phospho.ELM 9.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated16396499; 16381945; 23193290; 22135298; 19366988; 22673903;
224SPGTPAKTPQPNAFPPhosphoSitePlus22135298
277EQLPGPGSPGHGTADdbPTM 3.0;PhosphoSitePlus;curated15834132; 18762583; 16381945; 23193290; 22135298; 22817900
363HERGGEATWSGSEFEcurated23712012; 21630457
365RGGEATWSGSEFEISPhosphoSitePlus;UniProt;curated22135298; 22673903; 23712012; 21630457
367GEATWSGSEFEISFPPhosphoSitePlus;UniProt;curated22135298; 22673903; 23712012; 21630457
372SGSEFEISFPDSPGScurated23712012; 21630457
376FEISFPDSPGSQAQVPhosphoSitePlus;curated22135298; 23712012; 21630457
Sequence
(Fasta)		MGLGASSEQP AGGEGFHLHG VQENSPAQQA GLEPYFDFII TIGHSRLNKE NDTLKALLKA 60
NVEKPVKLEV FNMKTMRVRE VEVVPSNMWG GQGLLGASVR FCSFRRASEH VWHVLDVEPS 120
SPAALAGLRP YTDYIVGSDQ ILQESEDFFT LIESHEGKPL KLMVYNSESD SCREVTVTPN 180
AAWGGEGSLG CGIGYGYLHR IPTQPSSQYK KPPSASSPGT PAKTPQPNAF PLGAPPPWPI 240
PQDSSGPELG SRQSDYMEAL PQVPGGFMEE QLPGPGSPGH GTADYGGCLH SMEIPLQPPP 300
PVQRVMDPGF LDVSGMSLLD SNNTSVCPSL SSSSLLTPTA VSALGPEDIG SSSSSHERGG 360
EATWSGSEFE ISFPDSPGSQ AQVDHLPRLT LPDGLTSAAS PEEGLSAELL EAQTEEPAHT 420
ASLDCMAQTE GPAGQVQAAP DPEPGLCEGP W 452
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0333--Golgi apparatus
KW-0449--Lipoprotein
KW-0472--Membrane
KW-0519--Myristate
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
Interpro

IPR024958--GRASP55/65_PDZ
IPR007583--GRASP55_65
IPR001478--PDZ
PROSITE
Pfam

PF04495--GRASP55_65
Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0000139--C:Golgi membrane
GO:0007030--P:Golgi organization
GO:0050774--P:negative regulation of dendrite morphogenesis
GO:0015031--P:protein transport