dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001153
Uniprot Accession O35179; SH3G2_RAT;
Genbank Protein ID NP_446387.1;
Genbank Nucleotide ID NM_053935.1;
Protein Name Endophilin-A1
Protein Synonyms/Alias Endophilin-1;SH3 domain protein 2A;SH3 domain-containing GRB2-like protein 2;SH3p4;
Gene Name Sh3gl2
Gene Synonyms/Alias Sh3d2a;Sh3p4;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)		 Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
75LSMINTMSKIRGQEKPhosphoSitePlus22135298
Sequence
(Fasta)		MSVAGLKKQF HKATQKVSEK VGGAEGTKLD DDFKEMERKV DVTSRAVMEI MTKTIEYLQP 60
NPASRAKLSM INTMSKIRGQ EKGPGYPQAE ALLAEAMLKF GRELGDDCNF GPALGEVGEA 120
MRELSEVKDS LDMEVKQNFI DPLQNLHDKD LREIQHHLKK LEGRRLDFDY KKKRQGKIPD 180
EELRQALEKF DESKEIAESS MFNLLEMDIE QVSQLSALVQ AQLEYHKQAV QILQQVTVRL 240
EERIRQASSQ PRREYQPKPR MSLEFATGDG TQPNGGLSHT GTPKPAGVQM DQPCCRALYD 300
FEPENEGELG FKEGDIITLT NQIDENWYEG MLHGQSGFFP INYVEILVAL PH 353
Keyword

KW-0002--3D-structure
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0254--Endocytosis
KW-0446--Lipid-binding
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0728--SH3 domain
Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR001452--SH3_domain
IPR013315--Spectrin_alpha_SH3
PROSITE

PS51021--BAR
PS50002--SH3
Pfam

PF03114--BAR
PF00018--SH3_1
Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005886--C:plasma membrane
GO:0008289--F:lipid binding
GO:0002090--P:regulation of receptor internalization
GO:0048488--P:synaptic vesicle endocytosis