dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0001131 |
| Uniprot Accession | O35095; NCDN_RAT; Q5PQW2; |
| Genbank Protein ID | NP_445995.2; |
| Genbank Nucleotide ID | NM_053543.2; |
| Protein Name | Neurochondrin |
| Protein Synonyms/Alias | Neurite outgrowth-related protein from the rat brain;Norbin; |
| Gene Name | Ncdn |
| Gene Synonyms/Alias | |
| Organism | Rattus norvegicus(Rat) |
| NCBI Taxa ID | 10116 |
| Functional Description (View all) |
Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling. Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin-concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth. |
| Phosphorylation Sites |
dbPAF PTMs: 4 |
| Sequence (Fasta) | MSCCDLAAAG QLGKAGIMAS DCEPALNQAE SRNPTLERYL GALREAKNDS EQFAALLLVT 60 KAVKAGDIDA KTRRRIFDAV GFTFPNRLLT TKEAPDGCPD HVLRALGVAL LACFCSDPEL 120 ASHPQVLNKI PILCTFLTAR GDPDDAARRS MIDDTYQCLT AVAGTPRGPR HLIAGGTVSA 180 LCQAYLGHGY GFDQALALLV GLLAAAETQC WKEAEPDLLA VLRGLSEDFQ RAEDASKFEL 240 CQLLPLFLPP TTVPPECHRD LQAGLARILG SKLSSWQRNP ALKLAARLAH ACGSDWIPVG 300 SSGSKFLALL VNLACVEVRL ALEETGTEVK EDVVTACYAL MELGIQECTR CEQSLLKEPQ 360 KVQLVSIMKE AIGAVIHYLL RVGPEKQKEP FVFASVRILG AWLAEETSSL RKEVCQLLPF 420 LVRYAKTLYE EAEEASDISQ QVANLAISPT TPGPAWPGDA LRLLLPGWCH LTVEDGPREI 480 LIKEGAPSLL CKYFLQQWEL TSPGHDTSVL PDSVEIGLQT CCHIFLNLVV TAPGLIKRDA 540 CFTSLMNTLM TSLPSLVQQQ GRLLLAANVA TLGLLMARLL STSPALQGTP ASRGFFAAAI 600 LFLSQSHVAR ATPGSDQAVL ALSPDYEGIW ADLQELWFLG MQAFTGCVPL LPWLAPAALR 660 SRWPQELLQL LGSVSPNSVK PEMVAAYQGV LVELARANRL CREAMRLQAG EETASHYRMA 720 ALEQCLSEP |
| Keyword | KW-0007--Acetylation |
| Interpro | |
| PROSITE | |
| Pfam | PF05536--Neurochondrin |
| Gene Ontology | GO:0005829--C:cytosol |