dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001123
Uniprot Accession O35071; KIF1C_MOUSE; Q5SX62;
Genbank Protein ID NP_694743.2; XP_006532383.1; XP_006532384.1; XP_006532385.1;
Genbank Nucleotide ID NM_153103.2; XM_006532320.2; XM_006532321.2; XM_006532322.2;
Protein Name Kinesin-like protein KIF1C
Protein Synonyms/Alias
Gene Name Kif1c
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)		 Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end-directed motility (By similarity).
Phosphorylation Sites
 dbPAF PTMs: 28 (View all)
PositionPeptidesSourceReferences ( PMIDs )
204DCGNKARTVAATNMNPhosphoSitePlus;curated22135298; 22817900
295LQSKKRKSDFIPYRDdbPTM 3.0;PhosphoSitePlus22067460; 16381945; 23193290; 22135298
338NYEETLSTLRYADRTPhosphoSitePlus22135298
405GGVLPPASSPPAPAScurated25338131
412SSPPAPASPSSPPPHcurated25338131
414PPAPASPSSPPPHNGcurated25338131
415PAPASPSSPPPHNGEcurated25338131
494GGTVGVFSPKKTPHLPhosphoSitePlus;curated22135298; 25338131
671LLEQQRLYADSDSGEdbPTM 3.0;PhosphoSitePlus;SysPTM 2.020531401; 16381945; 23193290; 17242355; 22135298; 19366988
674QQRLYADSDSGEDSDdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated17242355; 19367708; 16381945; 23193290; 18846507; 20415495;
676RLYADSDSGEDSDKRdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated17242355; 19367708; 16381945; 23193290; 18846507; 20415495;
680DSDSGEDSDKRSCEEdbPTM 3.0;PHOSIDA;PhosphoSitePlus;curated20531401; 21183079; 16381945; 23193290; 21081558; 22135298;
907ETVPNDHSPAVRPTScurated25338131
913HSPAVRPTSPPLSSWcurated25338131
982KLRFPFKSNPQHREScurated23684622
989SNPQHRESWPGMGSGcurated23684622
1020PPNRRPPSPRRPHRSdbPTM 3.0;PhosphoPep 2.0;PhosphoSitePlus;curated21183079; 16381945; 23193290; 19060867; 22135298; 22817900
1027SPRRPHRSRRNSLDGdbPTM 3.0;PHOSIDA;PhosphoSitePlus19367708; 16381945; 23193290; 21081558; 22135298
1031PHRSRRNSLDGGSRSdbPTM 3.0;PHOSIDA;PhosphoSitePlus;SysPTM 2.0;curated19367708; 16381945; 23193290; 18846507; 20415495; 21081558;
1036RNSLDGGSRSRGGGSPhosphoSitePlus;curated22135298; 25266776
Sequence
(Fasta)		MAGASVKVAV RVRPFNARET SQDAKCVVSM QGNTTSIINP KQSKDAPKSF TFDYSYWSHT 60
SVEDPQFASQ QQVYRDIGEE MLLHAFEGYN VCIFAYGQTG AGKSYTMMGR QEPGQQGIVP 120
QLCEDLFSRV NVNQSAQLSY SVEVSYMEIY CERVRDLLNP KSRGSLRVRE HPILGPYVQD 180
LSKLAVTSYA DIADLMDCGN KARTVAATNM NETSSRSHAV FTIVFTQRSH DQLTGLDSEK 240
VSKISLVDLA GSERADSSGA RGMRLKEGAN INKSLTTLGK VISALADLQS KKRKSDFIPY 300
RDSVLTWLLK ENLGGNSRTA MIAALSPADI NYEETLSTLR YADRTKQIRC NAVINEDPNA 360
RLIRELQEEV ARLRDLLMAQ GLSASALGGL KVEEGSPGGV LPPASSPPAP ASPSSPPPHN 420
GELEPSFSPS AEPQIGPEEA MERLQETEKI IAELNETWEE KLRKTEALRM EREALLAEMG 480
VAVREDGGTV GVFSPKKTPH LVNLNEDPLM SECLLYHIKD GVTRVGQVDV DIKLTGQFIR 540
EQHCLFRSIP QPDGEVMVTL EPCEGAETYV NGKLVTEPLV LKSGNRIVMG KNHVFRFNHP 600
EQARLERERG VPPPPGPPSE PVDWNFAQKE LLEQQGIDIK LEMEKRLQDL ENQYRKEKEE 660
ADLLLEQQRL YADSDSGEDS DKRSCEESWR LISSLREQLP PTTVQNIVKR CGLPSSGKRR 720
APRRVYQIPQ RRRLQGKDPR WATMADLKMQ AVKEICYEVA LADFRHGRAE IEALAALKMR 780
ELCRTYGKPE GPGDAWRAVA RDVWDTVGEE EGCGGGGGGS EEGARGAEVE DLRAHIDKLT 840
GILQEVKLQN SSKDRELQAL RDRMLRMERV IPLTQDLEDD NDESGLVTWA PPEGPEAVEE 900
TVPNDHSPAV RPTSPPLSSW ERVSRLMEED PAFRRGRLRW LKQEQLRLQG LQGAGGRGGG 960
LRRPPARFVP PHDCKLRFPF KSNPQHRESW PGMGSGEAPA PQPPEEVTVP PAPPNRRPPS 1020
PRRPHRSRRN SLDGGSRSRG GGSTQPEPQH LRPQKHNGYP QQPQPSPAQR PGPRYPPYTT 1080
PPRMRRQRSA PDLKESGAAV 1101
Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR000253--FHA_dom
IPR027640--Kinesin-like_fam
IPR032405--Kinesin_assoc
IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR008984--SMAD_FHA_domain
PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
Pfam

PF00498--FHA
PF00225--Kinesin
PF16183--Kinesin_assoc
Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0005871--C:kinesin complex
GO:0005874--C:microtubule
GO:0005524--F:ATP binding
GO:0008574--F:ATP-dependent microtubule motor activity, plus-end-directed
GO:0044822--F:poly(A) RNA binding
GO:0030705--P:cytoskeleton-dependent intracellular transport
GO:0007018--P:microtubule-based movement
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER