Tag |
Content |
dbPAF ID |
dbPAF-0001121 |
Uniprot Accession |
O35054; CLD4_MOUSE; |
Genbank Protein ID |
NP_034033.1; |
Genbank Nucleotide ID |
NM_009903.2; |
Protein Name |
Claudin-4 |
Protein Synonyms/Alias |
Clostridium perfringens enterotoxin receptor;CPE-R;CPE-receptor; |
Gene Name |
Cldn4 |
Gene Synonyms/Alias |
Cper;Cpetr1; |
Organism |
Mus musculus(Mouse) |
NCBI Taxa ID |
10090 |
Functional Description (View all) |
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.Functional Description
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
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Phosphorylation Sites
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dbPAF PTMs: 3 |
Sequence (Fasta) | MASMGLQVLG ISLAVLGWLG IILSCALPMW RVTAFIGSNI VTAQTSWEGL WMNCVVQSTG 60 QMQCKMYDSM LALPQDLQAA RALMVISIIV GALGMLLSVV GGKCTNCMED ETVKAKIMIT 120 AGAVFIVASM LIMVPVSWTA HNVIRDFYNP MVASGQKREM GASLYVGWAA SGLLLLGGGL 180 LCCSCPPRSN DKPYSAKYSA ARSVPASNYV
211Fasta Sequence
>O35054|Cldn4|Mus musculus(Mouse) MASMGLQVLGISLAVLGWLGIILSCALPMWRVTAFIGSNIVTAQTSWEGLWMNCVVQSTGQMQCKMYDSMLALPQDLQAARALMVISIIVGALGMLLSVVGGKCTNCMEDETVKAKIMITAGAVFIVASMLIMVPVSWTAHNVIRDFYNPMVASGQKREMGASLYVGWAASGLLLLGGGLLCCSCPPRSNDKPYSAKYSAARSVPASNYV
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Keyword |
KW-0965--Cell junction KW-1003--Cell membrane KW-0181--Complete proteome KW-0472--Membrane KW-0597--Phosphoprotein KW-1185--Reference proteome KW-0796--Tight junction KW-0812--Transmembrane KW-1133--Transmembrane helix
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Interpro |
IPR006187--Claudin IPR003550--Claudin4 IPR017974--Claudin_CS IPR004031--PMP22/EMP/MP20/Claudin
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PROSITE |
PS01346--CLAUDIN
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Pfam |
PF00822--PMP22_Claudin
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Gene Ontology |
GO:0016324--C:apical plasma membrane GO:0016327--C:apicolateral plasma membrane GO:0009925--C:basal plasma membrane GO:0005923--C:bicellular tight junction GO:0016021--C:integral component of membrane GO:0005887--C:integral component of plasma membrane GO:0016328--C:lateral plasma membrane GO:0005886--C:plasma membrane GO:0042802--F:identical protein binding GO:0005198--F:structural molecule activity GO:0016338--P:calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules GO:0007623--P:circadian rhythm GO:0061436--P:establishment of skin barrier GO:0007565--P:female pregnancy GO:0032570--P:response to progesterone
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