dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0001120 |
| Uniprot Accession | O35052; CDS1_RAT; A0JPL6; O88208; |
| Genbank Protein ID | NP_112521.2; |
| Genbank Nucleotide ID | NM_031242.2; |
| Protein Name | Phosphatidate cytidylyltransferase 1 |
| Protein Synonyms/Alias | CDP-DAG synthase 1;CDP-DG synthase 1;CDP-diacylglycerol synthase 1;CDS 1;CDP-diglyceride pyrophosphorylase 1;CDP-diglyceride synthase 1;CTP:phosphatidate cytidylyltransferase 1; |
| Gene Name | Cds1 |
| Gene Synonyms/Alias | Cds; |
| Organism | Rattus norvegicus(Rat) |
| NCBI Taxa ID | 10116 |
| Functional Description (View all) |
Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin. Overexpression may amplify cellular signaling responses from cytokines. May also play an important role in the signal transduction mechanism of retina and neural cells (By similarity). May play an important role in phosphoinositide synthesis, prefers 1-stearoyl-2-arachidonoyl phosphatidic acid as substrate. |
| Phosphorylation Sites |
dbPAF PTMs: 4 |
| Sequence (Fasta) | MLELRHRGGC PGPGGAGTPP PREGEAAGGD HETESTSDKE TDIDDRYGDL DARGDSDVPE 60 VPPSSDRTPE ILKKALSGLS SRWKNWWIRG ILTLTMISLF FLIIYMGSFM LMLLVLGIQV 120 KCFQEIITIG YRVYHSYDLP WFRTLSWYFL LCVNYFFYGE TVADYFATFV QREEQLQFLI 180 RYHRFISFAL YLAGFCMFVL SLVKKHYRLQ FYMFAWTHVT LLITVTQSHL VIQNLFEGMI 240 WFLVPISSVI CNDITAYLFG FFFGRTPLIK LSPKKTWEGF IGGFFSTVIF GFIAAYVLSK 300 YQYFVCPVEY RSDVNSFVTE CEPSELFQLQ NYSLPPFLQA VLSRETVSLY PFQIHSIALS 360 TFASLIGPFG GFFASGFKRA FKIKDFANTI PGHGGIMDRF DCQYLMATFV HVYITSFIRG 420 PNPSKVLQQL LVLQPEQQLN IYRTLKIHLT EKGILQPTWK V 462 |
| Keyword | KW-0181--Complete proteome |
| Interpro | |
| PROSITE | PS01315--CDS |
| Pfam | |
| Gene Ontology | GO:0005789--C:endoplasmic reticulum membrane |