| Tag |
Content |
| dbPAF ID |
dbPAF-0001111 |
| Uniprot Accession |
O18388; IMB_DROME; Q540Y0; Q9V3E6;
|
| Genbank Protein ID |
NP_001246108.1; NP_001246109.1; NP_001246110.1; NP_001246111.1; NP_477496.1;
|
| Genbank Nucleotide ID |
NM_001259179.2; NM_001259180.2; NM_001259181.2; NM_001259182.2; NM_058148.5;
|
| Protein Name |
Importin subunit beta |
| Protein Synonyms/Alias |
Karyopherin subunit beta;Protein ketel; |
| Gene Name |
Fs(2)Ket |
| Gene Synonyms/Alias |
CG2637; |
| Organism |
Drosophila melanogaster(Fruit fly) |
| NCBI Taxa ID |
7227 |
Functional Description
(View all) |
Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins.Functional Description
Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. |
Phosphorylation Sites
|
dbPAF PTMs: 1 |
Sequence
(Fasta) | MTSDIAMQLI AILEKTVSPD KNELLSAKNF LEQAAASNLP EFLKALSEIL VNTANSAVAR 60
MAAGLQLKNH LTSKDEKVSQ QYQDRWHQFP SEIRELIKNN ILAALGTENT RPSCAAQCVA 120
YVAVIELPIN RWPMLIQTLV NKVVSEGSSE MHRESALEAI GYICQDIRFG VMENQSNDVL 180
TAIIHGMRKV EPSNHVRLAA TTALHNSLEF TKSNFEKDME RNFIMEVVCE ATQCQDSQIC 240
VAALQCLVKI MTLYYQYMEP YMAQALFPIT LAAMKSDNDA VALQGIEFWS NVCDEEIDLA 300
IESQEATDQG RAPQRVSKHY ARGALQFLTP VLVEKLTKQD ECDDEDTWSP AKAASVCLMV 360
LATCCEDEIV PHVLPFIKEN IESPNWRFRD AAVMTFGSVL NGLETNTLKP LVEQAMPTLI 420
RLMYDSSVIV RDTIAWTFGR ICDIIPEAAI NETYLQTLLE CFVKSLKSEP RVAANVCWAF 480
IGLSDAAWEA AVTNDGETPE TYALSPYFEY IITQLLETTD RSDGAQANLR CAAYQALMDM 540
IKNSPLDCYL VVQRTTLVIL ERLNQVMQME TQINNHSDRH QFNDLQSLLC ATLQSVLRKV 600
HEQDAPQISD AIMTALLTMF NSSAGKSGVV QEEAFLAVST LVELLGAQFA KYMPAFKDFL 660
VMGLKNFQEY QVCCAAVGLT GDIFRALKDL MVPYSNEIMT VLINNLTEPT IHRTVKPQVL 720
SAFGDIALSI GNHFLPYLSM VLDMLRVASN LQTDANNFDM NEYINELRES ILEAYTGIIQ 780
GLKGVDQTAH TDVMHMEPHL MHIISFIKRI AQEGDVSDSM LASAAGFIGD LCTSFGPRLY 840
PLLDDAIITQ FLAEGKRSKA QRTKMLCTWA VKEIKKINTQ VITQ
885Fasta Sequence
>O18388|Fs(2)Ket|Drosophila melanogaster(Fruit fly)
MTSDIAMQLIAILEKTVSPDKNELLSAKNFLEQAAASNLPEFLKALSEILVNTANSAVARMAAGLQLKNHLTSKDEKVSQQYQDRWHQFPSEIRELIKNNILAALGTENTRPSCAAQCVAYVAVIELPINRWPMLIQTLVNKVVSEGSSEMHRESALEAIGYICQDIRFGVMENQSNDVLTAIIHGMRKVEPSNHVRLAATTALHNSLEFTKSNFEKDMERNFIMEVVCEATQCQDSQICVAALQCLVKIMTLYYQYMEPYMAQALFPITLAAMKSDNDAVALQGIEFWSNVCDEEIDLAIESQEATDQGRAPQRVSKHYARGALQFLTPVLVEKLTKQDECDDEDTWSPAKAASVCLMVLATCCEDEIVPHVLPFIKENIESPNWRFRDAAVMTFGSVLNGLETNTLKPLVEQAMPTLIRLMYDSSVIVRDTIAWTFGRICDIIPEAAINETYLQTLLECFVKSLKSEPRVAANVCWAFIGLSDAAWEAAVTNDGETPETYALSPYFEYIITQLLETTDRSDGAQANLRCAAYQALMDMIKNSPLDCYLVVQRTTLVILERLNQVMQMETQINNHSDRHQFNDLQSLLCATLQSVLRKVHEQDAPQISDAIMTALLTMFNSSAGKSGVVQEEAFLAVSTLVELLGAQFAKYMPAFKDFLVMGLKNFQEYQVCCAAVGLTGDIFRALKDLMVPYSNEIMTVLINNLTEPTIHRTVKPQVLSAFGDIALSIGNHFLPYLSMVLDMLRVASNLQTDANNFDMNEYINELRESILEAYTGIIQGLKGVDQTAHTDVMHMEPHLMHIISFIKRIAQEGDVSDSMLASAAGFIGDLCTSFGPRLYPLLDDAIITQFLAEGKRSKAQRTKMLCTWAVKEIKKINTQVITQ
|
| Keyword |
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
|
| Interpro |
IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR021133--HEAT_type_2
IPR001494--Importin-beta_N
|
| PROSITE |
PS50077--HEAT_REPEAT
PS50166--IMPORTIN_B_NT
|
| Pfam |
PF03810--IBN_N
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0005811--C:lipid particle
GO:0005875--C:microtubule associated complex
GO:0005635--C:nuclear envelope
GO:0031965--C:nuclear membrane
GO:0034399--C:nuclear periphery
GO:0005643--C:nuclear pore
GO:0005654--C:nucleoplasm
GO:0043186--C:P granule
GO:0008139--F:nuclear localization sequence binding
GO:0008320--F:protein transmembrane transporter activity
GO:0008565--F:protein transporter activity
GO:0007015--P:actin filament organization
GO:0007304--P:chorion-containing eggshell formation
GO:0007067--P:mitotic nuclear division
GO:0006607--P:NLS-bearing protein import into nucleus
GO:0051533--P:positive regulation of NFAT protein import into nucleus
GO:0006606--P:protein import into nucleus
GO:0000059--P:protein import into nucleus, docking
GO:0000060--P:protein import into nucleus, translocation
GO:0071806--P:protein transmembrane transport
GO:0008360--P:regulation of cell shape
GO:0006610--P:ribosomal protein import into nucleus
|
