Tag |
Content |
dbPAF ID |
dbPAF-0001111 |
Uniprot Accession |
O18388; IMB_DROME; Q540Y0; Q9V3E6;
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Genbank Protein ID |
NP_001246108.1; NP_001246109.1; NP_001246110.1; NP_001246111.1; NP_477496.1;
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Genbank Nucleotide ID |
NM_001259179.2; NM_001259180.2; NM_001259181.2; NM_001259182.2; NM_058148.5;
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Protein Name |
Importin subunit beta |
Protein Synonyms/Alias |
Karyopherin subunit beta;Protein ketel; |
Gene Name |
Fs(2)Ket |
Gene Synonyms/Alias |
CG2637; |
Organism |
Drosophila melanogaster(Fruit fly) |
NCBI Taxa ID |
7227 |
Functional Description (View all) |
Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins.Functional Description
Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins.
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Phosphorylation Sites
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dbPAF PTMs: 1 |
Sequence (Fasta) | MTSDIAMQLI AILEKTVSPD KNELLSAKNF LEQAAASNLP EFLKALSEIL VNTANSAVAR 60 MAAGLQLKNH LTSKDEKVSQ QYQDRWHQFP SEIRELIKNN ILAALGTENT RPSCAAQCVA 120 YVAVIELPIN RWPMLIQTLV NKVVSEGSSE MHRESALEAI GYICQDIRFG VMENQSNDVL 180 TAIIHGMRKV EPSNHVRLAA TTALHNSLEF TKSNFEKDME RNFIMEVVCE ATQCQDSQIC 240 VAALQCLVKI MTLYYQYMEP YMAQALFPIT LAAMKSDNDA VALQGIEFWS NVCDEEIDLA 300 IESQEATDQG RAPQRVSKHY ARGALQFLTP VLVEKLTKQD ECDDEDTWSP AKAASVCLMV 360 LATCCEDEIV PHVLPFIKEN IESPNWRFRD AAVMTFGSVL NGLETNTLKP LVEQAMPTLI 420 RLMYDSSVIV RDTIAWTFGR ICDIIPEAAI NETYLQTLLE CFVKSLKSEP RVAANVCWAF 480 IGLSDAAWEA AVTNDGETPE TYALSPYFEY IITQLLETTD RSDGAQANLR CAAYQALMDM 540 IKNSPLDCYL VVQRTTLVIL ERLNQVMQME TQINNHSDRH QFNDLQSLLC ATLQSVLRKV 600 HEQDAPQISD AIMTALLTMF NSSAGKSGVV QEEAFLAVST LVELLGAQFA KYMPAFKDFL 660 VMGLKNFQEY QVCCAAVGLT GDIFRALKDL MVPYSNEIMT VLINNLTEPT IHRTVKPQVL 720 SAFGDIALSI GNHFLPYLSM VLDMLRVASN LQTDANNFDM NEYINELRES ILEAYTGIIQ 780 GLKGVDQTAH TDVMHMEPHL MHIISFIKRI AQEGDVSDSM LASAAGFIGD LCTSFGPRLY 840 PLLDDAIITQ FLAEGKRSKA QRTKMLCTWA VKEIKKINTQ VITQ
885Fasta Sequence
>O18388|Fs(2)Ket|Drosophila melanogaster(Fruit fly) MTSDIAMQLIAILEKTVSPDKNELLSAKNFLEQAAASNLPEFLKALSEILVNTANSAVARMAAGLQLKNHLTSKDEKVSQQYQDRWHQFPSEIRELIKNNILAALGTENTRPSCAAQCVAYVAVIELPINRWPMLIQTLVNKVVSEGSSEMHRESALEAIGYICQDIRFGVMENQSNDVLTAIIHGMRKVEPSNHVRLAATTALHNSLEFTKSNFEKDMERNFIMEVVCEATQCQDSQICVAALQCLVKIMTLYYQYMEPYMAQALFPITLAAMKSDNDAVALQGIEFWSNVCDEEIDLAIESQEATDQGRAPQRVSKHYARGALQFLTPVLVEKLTKQDECDDEDTWSPAKAASVCLMVLATCCEDEIVPHVLPFIKENIESPNWRFRDAAVMTFGSVLNGLETNTLKPLVEQAMPTLIRLMYDSSVIVRDTIAWTFGRICDIIPEAAINETYLQTLLECFVKSLKSEPRVAANVCWAFIGLSDAAWEAAVTNDGETPETYALSPYFEYIITQLLETTDRSDGAQANLRCAAYQALMDMIKNSPLDCYLVVQRTTLVILERLNQVMQMETQINNHSDRHQFNDLQSLLCATLQSVLRKVHEQDAPQISDAIMTALLTMFNSSAGKSGVVQEEAFLAVSTLVELLGAQFAKYMPAFKDFLVMGLKNFQEYQVCCAAVGLTGDIFRALKDLMVPYSNEIMTVLINNLTEPTIHRTVKPQVLSAFGDIALSIGNHFLPYLSMVLDMLRVASNLQTDANNFDMNEYINELRESILEAYTGIIQGLKGVDQTAHTDVMHMEPHLMHIISFIKRIAQEGDVSDSMLASAAGFIGDLCTSFGPRLYPLLDDAIITQFLAEGKRSKAQRTKMLCTWAVKEIKKINTQVITQ
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Keyword |
KW-0181--Complete proteome KW-0963--Cytoplasm KW-0653--Protein transport KW-1185--Reference proteome KW-0677--Repeat KW-0813--Transport
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Interpro |
IPR011989--ARM-like IPR016024--ARM-type_fold IPR021133--HEAT_type_2 IPR001494--Importin-beta_N
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PROSITE |
PS50077--HEAT_REPEAT PS50166--IMPORTIN_B_NT
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Pfam |
PF03810--IBN_N
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Gene Ontology |
GO:0005737--C:cytoplasm GO:0005811--C:lipid particle GO:0005875--C:microtubule associated complex GO:0005635--C:nuclear envelope GO:0031965--C:nuclear membrane GO:0034399--C:nuclear periphery GO:0005643--C:nuclear pore GO:0005654--C:nucleoplasm GO:0043186--C:P granule GO:0008139--F:nuclear localization sequence binding GO:0008320--F:protein transmembrane transporter activity GO:0008565--F:protein transporter activity GO:0007015--P:actin filament organization GO:0007304--P:chorion-containing eggshell formation GO:0007067--P:mitotic nuclear division GO:0006607--P:NLS-bearing protein import into nucleus GO:0051533--P:positive regulation of NFAT protein import into nucleus GO:0006606--P:protein import into nucleus GO:0000059--P:protein import into nucleus, docking GO:0000060--P:protein import into nucleus, translocation GO:0071806--P:protein transmembrane transport GO:0008360--P:regulation of cell shape GO:0006610--P:ribosomal protein import into nucleus
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