dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001110
Uniprot Accession O18373; SPS1_DROME; O18597; Q0E979; Q9V700;
Genbank Protein ID NP_725374.1; NP_725375.1;
Genbank Nucleotide ID NM_166045.2; NM_166046.2;
Protein Name Selenide, water dikinase
Protein Synonyms/Alias Protein patufet;Selenium donor protein;Selenophosphate synthase;dSelD;
Gene Name SelD
Gene Synonyms/Alias PTF1;ptuf;CG8553;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)		 Synthesizes selenophosphate from selenide and ATP. Essential for progression of the cell cycle by controlling the synthesis of selenoproteins. Plays a role in apoptosis and consequently a role in imaginal disk patterning and growth.
Phosphorylation Sites
 dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
2------MSYAADVLNPHOSIDA21081558
10YAADVLNSAHLELHGPHOSIDA;curated21081558; 22817900
37TAHDLDASFRLTRFAdbPTM 3.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;curated18327897; 16381945; 23193290; 21081558; 19060867; 19366988;
Sequence
(Fasta)		MSYAADVLNS AHLELHGGGD AELRRPFDPT AHDLDASFRL TRFADLKGRG CKVPQDVLSK 60
LVSALQQDYS AQDQEPQFLN VAIPRIGIGL DCSVIPLRHG GLCLVQTTDF FYPIVDDPYM 120
MGKIACANVL SDLYAMGVTD CDNMLMLLAV STKMTEKERD VVIPLIMRGF KDSALEAGTT 180
VTGGQSVVNP WCTIGGVAST ICQPNEYIVP DNAVVGDVLV LTKPLGTQVA VNAHQWIDQP 240
ERWNRIKLVV SEEDVRKAYH RAMNSMARLN RVAARLMHKY NAHGATDITG FGLLGHAQTL 300
AAHQKKDVSF VIHNLPVIAK MAAVAKACGN MFQLLQGHSA ETSGGLLICL PREQAAAYCK 360
DIEKQEGYQA WIIGIVEKGN KTARIIDKPR VIEVPAKD 399
Keyword

KW-0067--ATP-binding
KW-0131--Cell cycle
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0711--Selenium
KW-0808--Transferase
Interpro

IPR010918--AIR_synth_C_dom
IPR016188--PurM-like_N
IPR004536--SPS/SelD
PROSITE
Pfam

PF00586--AIRS
PF02769--AIRS_C
Gene Ontology

GO:0005524--F:ATP binding
GO:0016301--F:kinase activity
GO:0007049--P:cell cycle
GO:0008283--P:cell proliferation
GO:0006541--P:glutamine metabolic process
GO:0007444--P:imaginal disc development
GO:0007005--P:mitochondrion organization
GO:2000378--P:negative regulation of reactive oxygen species metabolic process
GO:0022008--P:neurogenesis
GO:0008284--P:positive regulation of cell proliferation
GO:0016260--P:selenocysteine biosynthetic process