dbPAF Protein Information
Tag | Content | ||||||||
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dbPAF ID | dbPAF-0001066 | ||||||||
Uniprot Accession | O17468; HIRA_DROME; O46105; O77144; Q5U0S5; Q8T0C3; Q9W3Q3; | ||||||||
Genbank Protein ID | NP_572401.2; | ||||||||
Genbank Nucleotide ID | NM_132173.3; | ||||||||
Protein Name | Protein HIRA homolog | ||||||||
Protein Synonyms/Alias | Protein sesame;dHIRA; | ||||||||
Gene Name | Hira | ||||||||
Gene Synonyms/Alias | Dhh;ssm;CG12153; | ||||||||
Organism | Drosophila melanogaster(Fruit fly) | ||||||||
NCBI Taxa ID | 7227 | ||||||||
Functional Description (View all) |
Required for the periodic repression of histone gene transcription during the cell cycle (By similarity). Required for replication-independent chromatin assembly. Promotes remodeling of sperm chromatin following fertilization via the incorporation of histone H3.3 and histone H4. | ||||||||
Phosphorylation Sites |
dbPAF PTMs: 1
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Sequence (Fasta) | MRLLKPAWVH HDDKQIFSVD IHKDCTKFAT GGQGSDCGRV VIWNLLPVLS DKAEFDADVP 60 KMLCQMDQHL ACVNCVRWSQ NGQNLASGSD DKLIMIWRKS AGSSGVFGTG GMQKNHESWK 120 CFYTLRGHDG DVLDLAWSPN DVYLASCSID NTVIIWDAQA FPHSVATLKG HTGLVKGVSW 180 DPLGRFLASQ SDDRSIKIWN TMNWSLSHTI TEPFEECGGT THILRLSWSP DGQYLVSAHA 240 MNGGGPTAQI IEREGWKCDK DFVGHRKAVT CVRFHNSILS RQENDGSPSK PLQYCCLAVG 300 SRDRSLSVWM TALQRPMVVI HELFNASILD LTWGPQECLL MACSVDGSIA CLKFTEEELG 360 KAISEEEQNA IIRKMYGKNY VNGLGKSAPV LEHPQRLLLP QGDKPTKFPL SNNNEANQRP 420 ISKQTETRTK DGKRRITPMF IPLHEDGPTS LSMNIVSSSG SSTTALTSCS AAIGTLPAAA 480 PTESAATPLM PLEPLVSKID LGRLDSRLKT QPASQRRQSL PFDPGQSNEL LRTPRLEEHQ 540 SSTCSPSNLN VTATGKSEFV KAALDYRLHV SNGHLKTQHG MLAKVTASDS KEMLWEFYVG 600 SPLVNLNLCE KYAMLCSLDG SMRLISMETG CPVFPAISLT SSAVHCAFSP DNSLVGVLTE 660 CGLLRIWDIA KKVVSLAAGC LELLNKHGTA AQFSVTNQGM PLIGFPSGNS YSYSTSLQSW 720 LVLATKDAIM YHGIRGTLPR DMDQMQQKFP LLSMQASSQN YFSFTGSMEL RHSESWQQCA 780 KIRFIENQIK LCEALQSLDE LQHWHKMLTF QLATHGSEKR MRVFLDDLLS MPEPGISQFV 840 PKLELMQCVL DTLKPHSEWN RLHSEYTELL KECKSERQKD IFATPAPPQQ KTASSAGSSP 900 RSGEATGEEV TEKDGATAVA AAVVAGSRMA VTTGTSTTTT TTASSSLSSS GSSSSTSGSG 960 SSSSSSSTSS LSVPQPAPSL SPEIQTLDSP TVCIDDEILS ASSSLPPLDT SPVEVSPAST 1020 SGGAASTSPA ASVAGSAPVS SSKTDQT 1048 |
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Keyword | KW-0025--Alternative splicing |
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Interpro | IPR020472--G-protein_beta_WD-40_rep |
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PROSITE | PS00678--WD_REPEATS_1 |
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Pfam | |||||||||
Gene Ontology | GO:0042585--C:germinal vesicle |