dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001012
Uniprot Accession O16102; CHD3_DROME; Q8SYJ8; Q9VVZ3;
Genbank Protein ID NP_649111.1;
Genbank Nucleotide ID NM_140854.3;
Protein Name Chromodomain-helicase-DNA-binding protein 3
Protein Synonyms/Alias ATP-dependent helicase Chd3;
Gene Name Chd3
Gene Synonyms/Alias CG9594;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)		 Possible transcription activator.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
63VYHRTCLSPPLKSIPPhosphoPep 2.0;curated19060867; 22817900
Sequence
(Fasta)		MSSKRGADPD WKTPGKASKD KRPKTNAKKQ KFRDEEYCKV CSDGGDLLCC DSCPSVYHRT 60
CLSPPLKSIP KGDWICPRCI PLPGKAEKIL SWRWALDRSV ELRTSKGEKR REYFIKWHGM 120
SYWHCEWIPE GQMLLHHASM VASFQRRSDM EEPSLEELDD QDGNLHERFY RYGIKPEWLL 180
VQRVINHSEE PNGGTMYLVK WRELSYNDSS WERESDSIPG LNQAIALYKK LRSSNKGRQR 240
DRPAPTIDLN KKYEDQPVFL KEAGLKLHPF QIEGVSWLRY SWGQGIPTIL ADEMGLGKTI 300
QTVVFLYSLF KEGHCRGPFL ISVPLSTLTN WERELELWAP ELYCVTYVGG KTARAVIRKH 360
EISFEEVTTK TMRENQTQYK FNVMLTSYEF ISVDAAFLGC IDWAALVVDE AHRLRSNQSK 420
FFRILSKYRI GYKLLLTGTP LQNNLEELFH LLNFLSSGKF NDLQTFQAEF TDVSKEEQVK 480
RLHEILEPHM LRRLKADVLK SMPPKSEFIV RVELSSMQKK FYKHILTKNF KALNQKGGGR 540
VCSLLNIMMD LRKCCNHPYL FPSAAEEATI SPSGLYEMSS LTKASGKLDL LSKMLKQLKA 600
DNHRVLLFSQ MTKMLNVLEH FLEGEGYQYD RIDGSIKGDL RQKAIDRFND PVSEHFVFLL 660
STRAGGLGIN LATADTVIIF DSDWNPHNDV QAFSRAHRMG QKKKVMIYRF VTHNSVEERI 720
MQVAKHKMML THLVVRPGMG GMTTNFSKDE LEDILRFGTE DLFKDGKSEA IHYDDKAVAD 780
LLDRTNRGIE EKESWANEYL SSFKVASYAT KEDHEEHDDY NNDAENTDPF YWENLMGKSQ 840
PKLPKKQKKQ SQQSQVDVES IMGKGKRIRK EIDYSNQYPS PNRATPSSIV LM 893
Keyword

KW-0010--Activator
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0347--Helicase
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR000953--Chromo/shadow_dom
IPR023780--Chromo_domain
IPR016197--Chromodomain-like
IPR002464--DNA/RNA_helicase_DEAH_CS
IPR009463--DUF1087
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
IPR019786--Zinc_finger_PHD-type_CS
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50013--CHROMO_2
PS00690--DEAH_ATP_HELICASE
PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF00385--Chromo
PF06465--DUF1087
PF00271--Helicase_C
PF00628--PHD
PF00176--SNF2_N
Gene Ontology

GO:0005634--C:nucleus
GO:0035327--C:transcriptionally active chromatin
GO:0005524--F:ATP binding
GO:0008026--F:ATP-dependent helicase activity
GO:0003677--F:DNA binding
GO:0004386--F:helicase activity
GO:0031491--F:nucleosome binding
GO:0070615--F:nucleosome-dependent ATPase activity
GO:0008270--F:zinc ion binding
GO:0006333--P:chromatin assembly or disassembly
GO:0042766--P:nucleosome mobilization
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated