| Tag |
Content |
| dbPAF ID |
dbPAF-0001010 |
| Uniprot Accession |
O16000; STX1A_CAEEL; O18657; O61526; Q9TZZ0;
|
| Genbank Protein ID |
NP_001022614.1; NP_001022615.1;
|
| Genbank Nucleotide ID |
NM_001027443.3; NM_001027444.3;
|
| Protein Name |
Syntaxin-1A homolog |
| Protein Synonyms/Alias |
Uncoordinated protein 64; |
| Gene Name |
unc-64 |
| Gene Synonyms/Alias |
F56A8.7; |
| Organism |
Caenorhabditis elegans |
| NCBI Taxa ID |
6239 |
Functional Description
(View all) |
Plays a critical role in several secretory processes, including cuticle secretion and neurotransmitter release, and probably assists in neuronal membrane maturation or the final stages of neuronal differentiation. Essential for embryonic viability and development. Has a role in dauer formation and adult life span. Required for locomotion.Functional Description
Plays a critical role in several secretory processes, including cuticle secretion and neurotransmitter release, and probably assists in neuronal membrane maturation or the final stages of neuronal differentiation. Essential for embryonic viability and development. Has a role in dauer formation and adult life span. Required for locomotion. |
Phosphorylation Sites
|
dbPAF PTMs: 2 |
Sequence
(Fasta) | MTKDRLSALK AAQSEDEQDD DMHMDTGNAQ YMEEFFEQVE EIRGSVDIIA NNVEEVKKKH 60
SAILSNPVND QKTKEELDEL MAVIKRAANK VRGKLKLIEN AIDHDEQGAG NADLRIRKTQ 120
HSTLSRRFVE VMTDYNKTQT DYRERCKGRI QRQLDIAGKQ VGDEDLEEMI ESGNPGVFTQ 180
GIITDTQQAK QTLADIEARH NDIMKLESSI RELHDMFMDM AMLVESQGEM VDRIEYNVEH 240
AKEFVDRAVA DTKKAVQYQS KARRKKICIL VTGVILITGL IIFILFYAKV L
292Fasta Sequence
>O16000|unc-64|Caenorhabditis elegans
MTKDRLSALKAAQSEDEQDDDMHMDTGNAQYMEEFFEQVEEIRGSVDIIANNVEEVKKKHSAILSNPVNDQKTKEELDELMAVIKRAANKVRGKLKLIENAIDHDEQGAGNADLRIRKTQHSTLSRRFVEVMTDYNKTQTDYRERCKGRIQRQLDIAGKQVGDEDLEEMIESGNPGVFTQGIITDTQQAKQTLADIEARHNDIMKLESSIRELHDMFMDMAMLVESQGEMVDRIEYNVEHAKEFVDRAVADTKKAVQYQSKARRKKICILVTGVILITGLIIFILFYAKVL
|
| Keyword |
KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0193--Cuticle
KW-0217--Developmental protein
KW-0221--Differentiation
KW-0472--Membrane
KW-0524--Neurogenesis
KW-0532--Neurotransmitter transport
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
|
| Interpro |
IPR028669--STX1A/1B
IPR006012--Syntaxin/epimorphin_CS
IPR006011--Syntaxin_N
IPR010989--t-SNARE
IPR000727--T_SNARE_dom
|
| PROSITE |
PS00914--SYNTAXIN
PS50192--T_SNARE
|
| Pfam |
PF05739--SNARE
PF00804--Syntaxin
|
| Gene Ontology |
GO:0030424--C:axon
GO:0016323--C:basolateral plasma membrane
GO:0030425--C:dendrite
GO:0012505--C:endomembrane system
GO:0016021--C:integral component of membrane
GO:0016020--C:membrane
GO:0043025--C:neuronal cell body
GO:0005886--C:plasma membrane
GO:0031201--C:SNARE complex
GO:0008021--C:synaptic vesicle
GO:0051087--F:chaperone binding
GO:0005484--F:SNAP receptor activity
GO:0000149--F:SNARE binding
GO:0042302--F:structural constituent of cuticle
GO:0019722--P:calcium-mediated signaling
GO:0030154--P:cell differentiation
GO:0006887--P:exocytosis
GO:0008286--P:insulin receptor signaling pathway
GO:0006886--P:intracellular protein transport
GO:0040011--P:locomotion
GO:0007399--P:nervous system development
GO:0007269--P:neurotransmitter secretion
GO:0017157--P:regulation of exocytosis
GO:0040014--P:regulation of multicellular organism growth
GO:0007268--P:synaptic transmission
GO:0007271--P:synaptic transmission, cholinergic
GO:0031629--P:synaptic vesicle fusion to presynaptic membrane
GO:0048278--P:vesicle docking
|
