dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001008
Uniprot Accession O15945; ARNT_DROME; O16167; O44082; Q24461; Q9VHI2;
Genbank Protein ID NP_001262397.1; NP_731308.1;
Genbank Nucleotide ID NM_001275468.1; NM_169254.2;
Protein Name Aryl hydrocarbon receptor nuclear translocator homolog
Protein Synonyms/Alias
Gene Name tgo
Gene Synonyms/Alias ARNT;HIF-1-beta;CG11987;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Heterodimers of tgo/trh are involved in the control of breathless expression. Plays a role in the cellular or tissue response to oxygen deprivation.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
214NRLKQRNSLGPSRDGcurated22817900
Sequence
(Fasta)
MDEANIQDKE RFASRENHCE IERRRRNKMT AYITELSDMV PTCSALARKP DKLTILRMAV 60
AHMKALRGTG NTSSDGTYKP SFLTDQELKH LILEAADGFL FVVSCDSGRV IYVSDSVTPV 120
LNYTQSDWYG TSLYEHIHPD DREKIREQLS TQESQNAGRI LDLKSGTVKK EGHQSSMRLS 180
MGARRGFICR MRVGNVNPES MVSGHLNRLK QRNSLGPSRD GTNYAVVHCT GYIKNWPPTD 240
MFPNMHMERD VDDMSSHCCL VAIGRLQVTS TAANDMSGSN NQSEFITRHA MDGKFTFVDQ 300
RVLNILGYTP TELLGKICYD FFHPEDQSHM KESFDQVLKQ KGQMFSLLYR ARAKNSEYVW 360
LRTQAYAFLN PYTDEVEYIV CTNSSGKTMH GAPLDAAAAH TPEQVQQQQQ QEQHVYVQAA 420
PGVDYARREL TPVGSATNDG MYQTHMLAMQ APTPQQQQQQ QQRPGSAQTT PVGYTYDTTH 480
SPYSAGGPSP LAKIPKSGTS PTPVAPNSWA ALRPQQQQQQ QQPVTEGYQY QQTSPARSPS 540
GPTYTQLSAG NGNRQQAQPG AYQAGPPPPP NAPGMWDWQQ AGGHPHPPHP TAHPHHPHAH 600
PGGPAGAGQP QGQEFSDMLQ MLDHTPTTFE DLNINMFSTP FE 643
Keyword

KW-0010--Activator
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR011598--bHLH_dom
IPR001067--Nuc_translocat
IPR001610--PAC
IPR000014--PAS
IPR013767--PAS_fold

PROSITE

PS50888--BHLH
PS50112--PAS

Pfam

PF00010--HLH
PF00989--PAS

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0043234--C:protein complex
GO:0005667--C:transcription factor complex
GO:0017022--F:myosin binding
GO:0046982--F:protein heterodimerization activity
GO:0000981--F:RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0007420--P:brain development
GO:0071456--P:cellular response to hypoxia
GO:0032869--P:cellular response to insulin stimulus
GO:0007417--P:central nervous system development
GO:0048813--P:dendrite morphogenesis
GO:0007425--P:epithelial cell fate determination, open tracheal system
GO:0008347--P:glial cell migration
GO:0060173--P:limb development
GO:0007517--P:muscle organ development
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0048666--P:neuron development
GO:0048477--P:oogenesis
GO:0007424--P:open tracheal system development
GO:0007422--P:peripheral nervous system development
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0045676--P:regulation of R7 cell differentiation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006366--P:transcription from RNA polymerase II promoter