Tag |
Content |
dbPAF ID |
dbPAF-0001008 |
Uniprot Accession |
O15945; ARNT_DROME; O16167; O44082; Q24461; Q9VHI2; |
Genbank Protein ID |
NP_001262397.1; NP_731308.1; |
Genbank Nucleotide ID |
NM_001275468.1; NM_169254.2; |
Protein Name |
Aryl hydrocarbon receptor nuclear translocator homolog |
Protein Synonyms/Alias |
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Gene Name |
tgo |
Gene Synonyms/Alias |
ARNT;HIF-1-beta;CG11987; |
Organism |
Drosophila melanogaster(Fruit fly) |
NCBI Taxa ID |
7227 |
Functional Description (View all) |
Heterodimers of tgo/trh are involved in the control of breathless expression. Plays a role in the cellular or tissue response to oxygen deprivation.Functional Description
Heterodimers of tgo/trh are involved in the control of breathless expression. Plays a role in the cellular or tissue response to oxygen deprivation.
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Phosphorylation Sites
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dbPAF PTMs: 1 Position | Peptides | Source | References ( PMIDs ) |
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214 | NRLKQRNSLGPSRDG | curated | 22817900 |
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Sequence (Fasta) | MDEANIQDKE RFASRENHCE IERRRRNKMT AYITELSDMV PTCSALARKP DKLTILRMAV 60 AHMKALRGTG NTSSDGTYKP SFLTDQELKH LILEAADGFL FVVSCDSGRV IYVSDSVTPV 120 LNYTQSDWYG TSLYEHIHPD DREKIREQLS TQESQNAGRI LDLKSGTVKK EGHQSSMRLS 180 MGARRGFICR MRVGNVNPES MVSGHLNRLK QRNSLGPSRD GTNYAVVHCT GYIKNWPPTD 240 MFPNMHMERD VDDMSSHCCL VAIGRLQVTS TAANDMSGSN NQSEFITRHA MDGKFTFVDQ 300 RVLNILGYTP TELLGKICYD FFHPEDQSHM KESFDQVLKQ KGQMFSLLYR ARAKNSEYVW 360 LRTQAYAFLN PYTDEVEYIV CTNSSGKTMH GAPLDAAAAH TPEQVQQQQQ QEQHVYVQAA 420 PGVDYARREL TPVGSATNDG MYQTHMLAMQ APTPQQQQQQ QQRPGSAQTT PVGYTYDTTH 480 SPYSAGGPSP LAKIPKSGTS PTPVAPNSWA ALRPQQQQQQ QQPVTEGYQY QQTSPARSPS 540 GPTYTQLSAG NGNRQQAQPG AYQAGPPPPP NAPGMWDWQQ AGGHPHPPHP TAHPHHPHAH 600 PGGPAGAGQP QGQEFSDMLQ MLDHTPTTFE DLNINMFSTP FE
643Fasta Sequence
>O15945|tgo|Drosophila melanogaster(Fruit fly) MDEANIQDKERFASRENHCEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVAHMKALRGTGNTSSDGTYKPSFLTDQELKHLILEAADGFLFVVSCDSGRVIYVSDSVTPVLNYTQSDWYGTSLYEHIHPDDREKIREQLSTQESQNAGRILDLKSGTVKKEGHQSSMRLSMGARRGFICRMRVGNVNPESMVSGHLNRLKQRNSLGPSRDGTNYAVVHCTGYIKNWPPTDMFPNMHMERDVDDMSSHCCLVAIGRLQVTSTAANDMSGSNNQSEFITRHAMDGKFTFVDQRVLNILGYTPTELLGKICYDFFHPEDQSHMKESFDQVLKQKGQMFSLLYRARAKNSEYVWLRTQAYAFLNPYTDEVEYIVCTNSSGKTMHGAPLDAAAAHTPEQVQQQQQQEQHVYVQAAPGVDYARRELTPVGSATNDGMYQTHMLAMQAPTPQQQQQQQQRPGSAQTTPVGYTYDTTHSPYSAGGPSPLAKIPKSGTSPTPVAPNSWAALRPQQQQQQQQPVTEGYQYQQTSPARSPSGPTYTQLSAGNGNRQQAQPGAYQAGPPPPPNAPGMWDWQQAGGHPHPPHPTAHPHHPHAHPGGPAGAGQPQGQEFSDMLQMLDHTPTTFEDLNINMFSTPFE
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Keyword |
KW-0010--Activator KW-0181--Complete proteome KW-0238--DNA-binding KW-0539--Nucleus KW-1185--Reference proteome KW-0677--Repeat KW-0804--Transcription KW-0805--Transcription regulation
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Interpro |
IPR011598--bHLH_dom IPR001067--Nuc_translocat IPR001610--PAC IPR000014--PAS IPR013767--PAS_fold
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PROSITE |
PS50888--BHLH PS50112--PAS
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Pfam |
PF00010--HLH PF00989--PAS
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Gene Ontology |
GO:0005737--C:cytoplasm GO:0005634--C:nucleus GO:0043234--C:protein complex GO:0005667--C:transcription factor complex GO:0017022--F:myosin binding GO:0046982--F:protein heterodimerization activity GO:0000981--F:RNA polymerase II transcription factor activity, sequence-specific DNA binding GO:0043565--F:sequence-specific DNA binding GO:0003700--F:transcription factor activity, sequence-specific DNA binding GO:0007420--P:brain development GO:0071456--P:cellular response to hypoxia GO:0032869--P:cellular response to insulin stimulus GO:0007417--P:central nervous system development GO:0048813--P:dendrite morphogenesis GO:0007425--P:epithelial cell fate determination, open tracheal system GO:0008347--P:glial cell migration GO:0060173--P:limb development GO:0007517--P:muscle organ development GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter GO:0048666--P:neuron development GO:0048477--P:oogenesis GO:0007424--P:open tracheal system development GO:0007422--P:peripheral nervous system development GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter GO:0045676--P:regulation of R7 cell differentiation GO:0006357--P:regulation of transcription from RNA polymerase II promoter GO:0006355--P:regulation of transcription, DNA-templated GO:0006366--P:transcription from RNA polymerase II promoter
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