| Tag |
Content |
| dbPAF ID |
dbPAF-0001001 |
| Uniprot Accession |
O15547; P2RX6_HUMAN; F6V3D7; Q32MB6; Q58F04; Q6IC33; Q9UL50;
|
| Genbank Protein ID |
NP_001153026.1; NP_005437.2;
|
| Genbank Nucleotide ID |
NM_001159554.1; NM_005446.3;
|
| Protein Name |
P2X purinoceptor 6 |
| Protein Synonyms/Alias |
|
| Gene Name |
P2RX6 |
| Gene Synonyms/Alias |
P2RXL1;P2X6; |
| Organism |
Homo sapiens(Human) |
| NCBI Taxa ID |
9606 |
Functional Description
(View all) |
Receptor for ATP that acts as a ligand-gated ion channel.Functional Description
Receptor for ATP that acts as a ligand-gated ion channel. |
Phosphorylation Sites
|
dbPAF PTMs: 3 |
Sequence
(Fasta) | MCPQLAGAGS MGSPGATTGW GLLDYKTEKY VMTRNWRVGA LQRLLQFGIV VYVVGWALLA 60
KKGYQERDLE PQFSIITKLK GVSVTQIKEL GNRLWDVADF VKPPQGENVF FLVTNFLVTP 120
AQVQGRCPEH PSVPLANCWV DEDCPEGEGG THSHGVKTGQ CVVFNGTHRT CEIWSWCPVE 180
SGVVPSRPLL AQAQNFTLFI KNTVTFSKFN FSKSNALETW DPTYFKHCRY EPQFSPYCPV 240
FRIGDLVAKA GGTFEDLALL GGSVGIRVHW DCDLDTGDSG CWPHYSFQLQ EKSYNFRTAT 300
HWWEQPGVEA RTLLKLYGIR FDILVTGQAG KFGLIPTAVT LGTGAAWLGV VTFFCDLLLL 360
YVDREAHFYW RTKYEEAKAP KATANSVWRE LALASQARLA ECLRRSSAPA PTATAAGSQT 420
QTPGWPCPSS DTHLPTHSGS L
442Fasta Sequence
>O15547|P2RX6|Homo sapiens(Human)
MCPQLAGAGSMGSPGATTGWGLLDYKTEKYVMTRNWRVGALQRLLQFGIVVYVVGWALLAKKGYQERDLEPQFSIITKLKGVSVTQIKELGNRLWDVADFVKPPQGENVFFLVTNFLVTPAQVQGRCPEHPSVPLANCWVDEDCPEGEGGTHSHGVKTGQCVVFNGTHRTCEIWSWCPVESGVVPSRPLLAQAQNFTLFIKNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQFSPYCPVFRIGDLVAKAGGTFEDLALLGGSVGIRVHWDCDLDTGDSGCWPHYSFQLQEKSYNFRTATHWWEQPGVEARTLLKLYGIRFDILVTGQAGKFGLIPTAVTLGTGAAWLGVVTFFCDLLLLYVDREAHFYWRTKYEEAKAPKATANSVWRELALASQARLAECLRRSSAPAPTATAAGSQTQTPGWPCPSSDTHLPTHSGSL
|
| Keyword |
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0325--Glycoprotein
KW-0407--Ion channel
KW-0406--Ion transport
KW-1071--Ligand-gated ion channel
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-0675--Receptor
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
|
| Interpro |
IPR003049--P2X6_purnocptor
IPR027309--P2X_extracellular_dom
IPR001429--P2X_purnocptor
|
| PROSITE |
PS01212--P2X_RECEPTOR
|
| Pfam |
PF00864--P2X_receptor
|
| Gene Ontology |
GO:0030054--C:cell junction
GO:0005737--C:cytoplasm
GO:0043197--C:dendritic spine
GO:0005639--C:integral component of nuclear inner membrane
GO:0005887--C:integral component of plasma membrane
GO:0043025--C:neuronal cell body
GO:0014069--C:postsynaptic density
GO:0005524--F:ATP binding
GO:0015267--F:channel activity
GO:0004931--F:extracellular ATP-gated cation channel activity
GO:0042802--F:identical protein binding
GO:0001614--F:purinergic nucleotide receptor activity
GO:0004888--F:transmembrane signaling receptor activity
GO:0006812--P:cation transport
GO:0034220--P:ion transmembrane transport
GO:0006936--P:muscle contraction
GO:0051291--P:protein heterooligomerization
GO:0051260--P:protein homooligomerization
GO:0035590--P:purinergic nucleotide receptor signaling pathway
GO:0033198--P:response to ATP
GO:0007165--P:signal transduction
GO:0006810--P:transport
|
