dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000996
Uniprot Accession O15537; XLRS1_HUMAN; Q0QD39;
Genbank Protein ID NP_000321.1;
Genbank Nucleotide ID NM_000330.3;
Protein Name Retinoschisin
Protein Synonyms/Alias X-linked juvenile retinoschisis protein;
Gene Name RS1
Gene Synonyms/Alias XLRS1;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
May be active in cell adhesion processes during retinal development.
Phosphorylation Sites
dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
105ANKARLNSQGFGCAWdbPTM 3.0;PhosphoSitePlus;curated20562096; 16381945; 23193290; 22135298; 22817900
114GFGCAWLSKFQDSSQdbPTM 3.0;PhosphoSitePlus;curated20562096; 16381945; 23193290; 22135298; 22817900
119WLSKFQDSSQWLQIDdbPTM 3.0;PhosphoSitePlus;curated20562096; 16381945; 23193290; 22135298; 22817900
177TGNNRVFYGNSDRTSdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated18491316; 16381945; 23193290; 18988627; 22135298; 22817900
183FYGNSDRTSTVQNLLdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated18491316; 16381945; 23193290; 18988627; 22135298; 22817900
Sequence
(Fasta)
MSRKIEGFLL LLLFGYEATL GLSSTEDEGE DPWYQKACKC DCQGGPNALW SAGATSLDCI 60
PECPYHKPLG FESGEVTPDQ ITCSNPEQYV GWYSSWTANK ARLNSQGFGC AWLSKFQDSS 120
QWLQIDLKEI KVISGILTQG RCDIDEWMTK YSVQYRTDER LNWIYYKDQT GNNRVFYGNS 180
DRTSTVQNLL RPPIISRFIR LIPLGWHVRI AIRMELLECV SKCA 225
Keyword

KW-0130--Cell adhesion
KW-0181--Complete proteome
KW-0225--Disease mutation
KW-1015--Disulfide bond
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0964--Secreted
KW-0716--Sensory transduction
KW-0732--Signal
KW-0844--Vision

Interpro

IPR000421--FA58C
IPR008979--Galactose-bd-like

PROSITE

PS01285--FA58C_1
PS50022--FA58C_3

Pfam

PF00754--F5_F8_type_C

Gene Ontology

GO:0005615--C:extracellular space
GO:0019897--C:extrinsic component of plasma membrane
GO:0005547--F:phosphatidylinositol-3,4,5-trisphosphate binding
GO:0043325--F:phosphatidylinositol-3,4-bisphosphate binding
GO:0080025--F:phosphatidylinositol-3,5-bisphosphate binding
GO:0032266--F:phosphatidylinositol-3-phosphate binding
GO:0005546--F:phosphatidylinositol-4,5-bisphosphate binding
GO:0070273--F:phosphatidylinositol-4-phosphate binding
GO:0010314--F:phosphatidylinositol-5-phosphate binding
GO:0001786--F:phosphatidylserine binding
GO:0016062--P:adaptation of rhodopsin mediated signaling
GO:0007155--P:cell adhesion
GO:0007275--P:multicellular organismal development
GO:0010842--P:retina layer formation
GO:0007601--P:visual perception