dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000988
Uniprot Accession O15522; NKX28_HUMAN; Q8IUT7;
Genbank Protein ID NP_055175.2;
Genbank Nucleotide ID NM_014360.2;
Protein Name Homeobox protein Nkx-2.8
Protein Synonyms/Alias Homeobox protein NK-2 homolog H;
Gene Name NKX2-8
Gene Synonyms/Alias NKX-2.8;NKX2G;NKX2H;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
66LETSPPDSSQRPSARcurated23898821
Sequence
(Fasta)		MATSGRLSFT VRSLLDLPEQ DAQHLPRREP EPRAPQPDPC AAWLDSERGH YPSSDESSLE 60
TSPPDSSQRP SARPASPGSD AEKRKKRRVL FSKAQTLELE RRFRQQRYLS APEREQLASL 120
LRLTPTQVKI WFQNHRYKLK RARAPGAAES PDLAASAELH AAPGLLRRVV VPVLVRDGQP 180
CGGGGGGEVG TAAAQEKCGA PPAAACPLPG YPAFGPGSAL GLFPAYQHLA SPALVSWNW 240
Keyword

KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0238--DNA-binding
KW-0371--Homeobox
KW-0539--Nucleus
KW-0621--Polymorphism
KW-1185--Reference proteome
Interpro

IPR017970--Homeobox_CS
IPR001356--Homeobox_dom
IPR020479--Homeobox_metazoa
IPR009057--Homeodomain-like
PROSITE

PS00027--HOMEOBOX_1
PS50071--HOMEOBOX_2
Pfam

PF00046--Homeobox
Gene Ontology

GO:0005634--C:nucleus
GO:0003690--F:double-stranded DNA binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0007409--P:axonogenesis
GO:0001889--P:liver development
GO:0030324--P:lung development
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0006366--P:transcription from RNA polymerase II promoter
GO:0006351--P:transcription, DNA-templated