| Tag |
Content |
| dbPAF ID |
dbPAF-0000983 |
| Uniprot Accession |
O15511; ARPC5_HUMAN; A6NEC4; Q6PG42;
|
| Genbank Protein ID |
NP_001257368.1; NP_005708.1;
|
| Genbank Nucleotide ID |
NM_001270439.1; NM_005717.3;
|
| Protein Name |
Actin-related protein 2/3 complex subunit 5 |
| Protein Synonyms/Alias |
Arp2/3 complex 16 kDa subunit;p16-ARC; |
| Gene Name |
ARPC5 |
| Gene Synonyms/Alias |
ARC16; |
| Organism |
Homo sapiens(Human) |
| NCBI Taxa ID |
9606 |
Functional Description
(View all) |
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.Functional Description
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. |
Phosphorylation Sites
|
dbPAF PTMs: 6 |
Sequence
(Fasta) | MSKNTVSSAR FRKVDVDEYD ENKFVDEEDG GDGQAGPDEG EVDSCLRQGN MTAALQAALK 60
NPPINTKSQA VKDRAGSIVL KVLISFKAND IEKAVQSLDK NGVDLLMKYI YKGFESPSDN 120
SSAMLLQWHE KALAAGGVGS IVRVLTARKT V
152Fasta Sequence
>O15511|ARPC5|Homo sapiens(Human)
MSKNTVSSARFRKVDVDEYDENKFVDEEDGGDGQAGPDEGEVDSCLRQGNMTAALQAALKNPPINTKSQAVKDRAGSIVLKVLISFKANDIEKAVQSLDKNGVDLLMKYIYKGFESPSDNSSAMLLQWHEKALAAGGVGSIVRVLTARKTV
|
| Keyword |
KW-0007--Acetylation
KW-0009--Actin-binding
KW-0025--Alternative splicing
KW-0966--Cell projection
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0903--Direct protein sequencing
KW-1185--Reference proteome
KW-0832--Ubl conjugation
|
| Interpro |
IPR006789--ARPC5
|
| PROSITE |
|
| Pfam |
PF04699--P16-Arc
|
| Gene Ontology |
GO:0015629--C:actin cytoskeleton
GO:0005885--C:Arp2/3 protein complex
GO:0042995--C:cell projection
GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0005200--F:structural constituent of cytoskeleton
GO:0030036--P:actin cytoskeleton organization
GO:0034314--P:Arp2/3 complex-mediated actin nucleation
GO:0007411--P:axon guidance
GO:0016477--P:cell migration
GO:0048013--P:ephrin receptor signaling pathway
GO:0038096--P:Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0045087--P:innate immune response
GO:0006928--P:movement of cell or subcellular component
GO:0007264--P:small GTPase mediated signal transduction
|
