dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000981
Uniprot Accession O15499; GSC2_HUMAN;
Genbank Protein ID NP_005306.1;
Genbank Nucleotide ID NM_005315.1;
Protein Name Homeobox protein goosecoid-2
Protein Synonyms/Alias
Gene Name GSC2
Gene Synonyms/Alias GSCL;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 May have a role in development. May regulate its own transcription. May bind the bicoid consensus sequence TAATCC.
Phosphorylation Sites
 dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
122PGAVGPGSQRRTRRHPhosphoSitePlus22135298
154QNQYPDVSTRERLAGPhosphoSitePlus22135298
155NQYPDVSTRERLAGRPhosphoSitePlus22135298
190HQKRASASARLLPGVPhosphoSitePlus22135298
Sequence
(Fasta)		MAAAAGGAAS RRGAGRPCPF SIEHILSSLP ERSLPARAAC PPQPAGRQSP AKPEEPGAPE 60
AAPCACCCCC GPRAAPCGPP EAAAGLGARL AWPLRLGPAV PLSLGAPAGG SGALPGAVGP 120
GSQRRTRRHR TIFSEEQLQA LEALFVQNQY PDVSTRERLA GRIRLREERV EVWFKNRRAK 180
WRHQKRASAS ARLLPGVKKS PKGSC 206
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0371--Homeobox
KW-0539--Nucleus
KW-0621--Polymorphism
KW-1185--Reference proteome
Interpro

IPR017970--Homeobox_CS
IPR001356--Homeobox_dom
IPR009057--Homeodomain-like
PROSITE

PS00027--HOMEOBOX_1
PS50071--HOMEOBOX_2
Pfam

PF00046--Homeobox
Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0009653--P:anatomical structure morphogenesis
GO:0006357--P:regulation of transcription from RNA polymerase II promoter